{"id":476,"date":"2026-05-19T22:43:39","date_gmt":"2026-05-19T19:43:39","guid":{"rendered":"https:\/\/novolakrb1.ru\/statii\/?page_id=476"},"modified":"2026-05-20T10:38:08","modified_gmt":"2026-05-20T07:38:08","slug":"mikrobiom-dyravyy-kishechnik","status":"publish","type":"page","link":"https:\/\/novolakrb1.ru\/statii\/mikrobiom-dyravyy-kishechnik\/","title":{"rendered":"\u041c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u043c \u043a\u0438\u0448\u0435\u0447\u043d\u0438\u043a\u0430, \u0434\u0438\u0441\u0431\u0438\u043e\u0437, \u0442\u0435\u0441\u0442\u044b \u043f\u0440\u043e\u0442\u043e\u043a\u043e\u043b \u0432\u043e\u0441\u0441\u0442\u0430\u043d\u043e\u0432\u043b\u0435\u043d\u0438\u044f"},"content":{"rendered":"\t\t<div data-elementor-type=\"wp-page\" data-elementor-id=\"476\" class=\"elementor elementor-476\">\n\t\t\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-1295faa5 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"1295faa5\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-6af5c8a4\" data-id=\"6af5c8a4\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-19b97bec elementor-widget elementor-widget-heading\" data-id=\"19b97bec\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h1 class=\"elementor-heading-title elementor-size-default\">\u041c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u043c \u043a\u0438\u0448\u0435\u0447\u043d\u0438\u043a\u0430 \u0438 \u0434\u044b\u0440\u044f\u0432\u044b\u0439 \u043a\u0438\u0448\u0435\u0447\u043d\u0438\u043a: \u0434\u0438\u0441\u0431\u0438\u043e\u0437, \u0442\u0435\u0441\u0442\u044b \u0438 \u043f\u0440\u043e\u0442\u043e\u043a\u043e\u043b \u0432\u043e\u0441\u0441\u0442\u0430\u043d\u043e\u0432\u043b\u0435\u043d\u0438\u044f<\/h1>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-33e5ee5e elementor-widget elementor-widget-text-editor\" data-id=\"33e5ee5e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p style=\"font-size: 13px; color: #64748b; margin: 0 0 24px 0;\"><br \/><a style=\"color: #3b82f6; text-decoration: none;\" href=\"\/\">\u0413\u043b\u0430\u0432\u043d\u0430\u044f<\/a> \u203a <a href=\"https:\/\/novolakrb1.ru\/statii\/\">\u0421\u0442\u0430\u0442\u044c\u0438<\/a> \u203a \u00a0<a style=\"color: #3b82f6; text-decoration: none;\" href=\"https:\/\/novolakrb1.ru\/statii\/zdorove-kishechnika\/\">\u0417\u0434\u043e\u0440\u043e\u0432\u044c\u0435 \u043a\u0438\u0448\u0435\u0447\u043d\u0438\u043a\u0430<\/a> \u203a <a style=\"color: #3b82f6; text-decoration: none;\" href=\"https:\/\/novolakrb1.ru\/statii\/dyravyy-kishechnik\/\">\u0414\u044b\u0440\u044f\u0432\u044b\u0439 \u043a\u0438\u0448\u0435\u0447\u043d\u0438\u043a<\/a> \u203a <span style=\"color: #64748b;\">\u041c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u043c<\/span><\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-403e272a elementor-widget elementor-widget-text-editor\" data-id=\"403e272a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p style=\"font-size:17px;line-height:1.75;color:#1E293B;font-weight:500;margin:0 0 14px 0;\">\u041c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u043c \u043a\u0438\u0448\u0435\u0447\u043d\u0438\u043a\u0430 \u2014 \u043d\u0435 \u043f\u0440\u043e\u0441\u0442\u043e \u00ab\u0441\u043e\u0436\u0438\u0442\u0435\u043b\u0438\u00bb, \u0430 \u0430\u043a\u0442\u0438\u0432\u043d\u044b\u0435 \u0443\u0447\u0430\u0441\u0442\u043d\u0438\u043a\u0438 \u043f\u043e\u0434\u0434\u0435\u0440\u0436\u0430\u043d\u0438\u044f \u0431\u0430\u0440\u044c\u0435\u0440\u043d\u043e\u0439 \u0444\u0443\u043d\u043a\u0446\u0438\u0438. \u0421\u043d\u0438\u0436\u0435\u043d\u0438\u0435 \u043a\u043b\u044e\u0447\u0435\u0432\u044b\u0445 \u041a\u0426\u0416\u041a-\u043f\u0440\u043e\u0434\u0443\u0446\u0435\u043d\u0442\u043e\u0432, \u0440\u043e\u0441\u0442 LPS-\u043f\u0440\u043e\u0434\u0443\u0446\u0438\u0440\u0443\u044e\u0449\u0438\u0445 \u0431\u0430\u043a\u0442\u0435\u0440\u0438\u0439, \u0443\u0442\u0440\u0430\u0442\u0430 Akkermansia muciniphila \u2014 \u0432\u0441\u0451 \u044d\u0442\u043e \u0437\u0430\u043f\u0443\u0441\u043a\u0430\u0435\u0442 \u0434\u044b\u0440\u044f\u0432\u044b\u0439 \u043a\u0438\u0448\u0435\u0447\u043d\u0438\u043a \u043d\u0430 \u043c\u043e\u043b\u0435\u043a\u0443\u043b\u044f\u0440\u043d\u043e\u043c \u0443\u0440\u043e\u0432\u043d\u0435. \u041d\u0430 \u044d\u0442\u043e\u0439 \u0441\u0442\u0440\u0430\u043d\u0438\u0446\u0435: \u043c\u0435\u0445\u0430\u043d\u0438\u0437\u043c \u0434\u0438\u0441\u0431\u0438\u043e\u0437\u2192leaky gut, \u0441\u0440\u0430\u0432\u043d\u0435\u043d\u0438\u0435 \u0442\u0435\u0441\u0442\u043e\u0432 2026, \u043b\u0443\u0447\u0448\u0438\u0435 \u043f\u0440\u043e\u0431\u0438\u043e\u0442\u0438\u043a\u0438 (\u0441 \u043c\u0435\u0442\u0430-\u0430\u043d\u0430\u043b\u0438\u0437\u043e\u043c) \u0438 gut-brain\/gut-skin axis.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4bb530aa elementor-widget elementor-widget-text-editor\" data-id=\"4bb530aa\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div style=\"background: #F0F9FF; border: 1px solid #BAE6FD; border-radius: 8px; padding: 12px 18px; margin-bottom: 10px;\"><p><span style=\"color: #0284c7; font-size: 15px; font-weight: 600;\">\u2192 <\/span><a style=\"color: #0284c7; font-size: 15px; font-weight: 600; text-decoration: none;\" href=\"https:\/\/novolakrb1.ru\/statii\/dyravyy-kishechnik\/\">\u2190 \u0412\u0435\u0440\u043d\u0443\u0442\u044c\u0441\u044f: \u0414\u044b\u0440\u044f\u0432\u044b\u0439 \u043a\u0438\u0448\u0435\u0447\u043d\u0438\u043a \u2014 \u043f\u043e\u043b\u043d\u044b\u0439 \u0433\u0438\u0434 2026<\/a><\/p><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-10e3a75e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"10e3a75e\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-1e5b643\" data-id=\"1e5b643\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7289cf97 elementor-widget elementor-widget-text-editor\" data-id=\"7289cf97\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p style=\"font-size:11px;font-weight:700;letter-spacing:2px;text-transform:uppercase;color:#64748B;margin:0 0 10px 0;\">\u0421\u043e\u0434\u0435\u0440\u0436\u0430\u043d\u0438\u0435<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4ef459df elementor-widget elementor-widget-text-editor\" data-id=\"4ef459df\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div style=\"background:#EFF6FF;border-left:4px solid #1E40AF;border-radius:0 8px 8px 0;padding:16px 20px;margin-bottom:16px;\"><ol style=\"padding-left:20px;margin:0;font-size:15px;line-height:2;color:#1E293B;\">\n      <li>\u0427\u0442\u043e \u0442\u0430\u043a\u043e\u0435 \u043c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u043c \u0438 \u043a\u0430\u043a \u043e\u043d \u043f\u043e\u0434\u0434\u0435\u0440\u0436\u0438\u0432\u0430\u0435\u0442 \u043a\u0438\u0448\u0435\u0447\u043d\u044b\u0439 \u0431\u0430\u0440\u044c\u0435\u0440<\/li>\n      <li>\u0414\u0438\u0441\u0431\u0438\u043e\u0437 \u043a\u0430\u043a \u043f\u0440\u0438\u0447\u0438\u043d\u0430 leaky gut: Firmicutes\/Bacteroidetes, LPS, \u041a\u0426\u0416\u041a<\/li>\n      <li>\u0422\u0435\u0441\u0442\u044b \u043c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u043c\u0430 2026: \u0441\u0440\u0430\u0432\u043d\u0435\u043d\u0438\u0435 Atlas, Genetico, InVivo, Helix<\/li>\n      <li>\u041b\u0443\u0447\u0448\u0438\u0435 \u0448\u0442\u0430\u043c\u043c\u044b \u043f\u0440\u043e\u0431\u0438\u043e\u0442\u0438\u043a\u043e\u0432 \u043f\u0440\u0438 \u0434\u044b\u0440\u044f\u0432\u043e\u043c \u043a\u0438\u0448\u0435\u0447\u043d\u0438\u043a\u0435<\/li>\n      <li>\u041f\u043e\u0441\u0442\u0431\u0438\u043e\u0442\u0438\u043a\u0438 \u0438 \u043f\u0440\u0435\u0431\u0438\u043e\u0442\u0438\u043a\u0438 \u0432 \u0432\u043e\u0441\u0441\u0442\u0430\u043d\u043e\u0432\u043b\u0435\u043d\u0438\u0438 \u0431\u0430\u0440\u044c\u0435\u0440\u0430<\/li>\n      <li>Gut-brain \u0438 gut-skin axis: \u0441\u0432\u044f\u0437\u044c \u043a\u0438\u0448\u0435\u0447\u043d\u0438\u043a\u0430 \u0441 \u043c\u043e\u0437\u0433\u043e\u043c \u0438 \u043a\u043e\u0436\u0435\u0439<\/li>\n      <li>FAQ<\/li>\n    <\/ol><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-205afbf4 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"205afbf4\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-228b7dad\" data-id=\"228b7dad\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-18fa2595 elementor-widget elementor-widget-heading\" data-id=\"18fa2595\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">1. \u0427\u0442\u043e \u0442\u0430\u043a\u043e\u0435 \u043c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u043c \u0438 \u043a\u0430\u043a \u043e\u043d \u043f\u043e\u0434\u0434\u0435\u0440\u0436\u0438\u0432\u0430\u0435\u0442 \u043a\u0438\u0448\u0435\u0447\u043d\u044b\u0439 \u0431\u0430\u0440\u044c\u0435\u0440<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-228d5bb1 elementor-widget elementor-widget-heading\" data-id=\"228d5bb1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">\u0421\u043e\u0441\u0442\u0430\u0432 \u0438 \u043c\u0430\u0441\u0448\u0442\u0430\u0431<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1e081c22 elementor-widget elementor-widget-text-editor\" data-id=\"1e081c22\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p style=\"font-size:16px;line-height:1.75;color:#1E293B;margin:0 0 14px 0;\">\u041a\u0438\u0448\u0435\u0447\u043d\u044b\u0439 \u043c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u043c \u2014 \u0441\u043e\u0432\u043e\u043a\u0443\u043f\u043d\u043e\u0441\u0442\u044c ~10\u00b9\u00b3 \u043c\u0438\u043a\u0440\u043e\u043e\u0440\u0433\u0430\u043d\u0438\u0437\u043c\u043e\u0432 (\u0431\u0430\u043a\u0442\u0435\u0440\u0438\u0438, \u0430\u0440\u0445\u0435\u0438, \u0433\u0440\u0438\u0431\u044b, \u0432\u0438\u0440\u0443\u0441\u044b), \u043d\u0430\u0441\u0435\u043b\u044f\u044e\u0449\u0438\u0445 \u0416\u041a\u0422 \u0447\u0435\u043b\u043e\u0432\u0435\u043a\u0430. \u0418\u0445 \u0441\u0443\u043c\u043c\u0430\u0440\u043d\u044b\u0439 \u0433\u0435\u043d\u043e\u043c (\u043c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u043c) \u0441\u043e\u0434\u0435\u0440\u0436\u0438\u0442 <b>>3 \u043c\u0438\u043b\u043b\u0438\u043e\u043d\u043e\u0432 \u0433\u0435\u043d\u043e\u0432<\/b> \u2014 \u0432 150 \u0440\u0430\u0437 \u0431\u043e\u043b\u044c\u0448\u0435, \u0447\u0435\u043c \u0433\u0435\u043d\u043e\u043c \u0445\u043e\u0437\u044f\u0438\u043d\u0430. \u0414\u043e\u043c\u0438\u043d\u0438\u0440\u0443\u044e\u0449\u0438\u0435 \u0442\u0438\u043f\u044b (\u0444\u0438\u043b\u0430): Firmicutes (~60%), Bacteroidetes (~25%), Proteobacteria (~5%), Actinobacteria (~3%).<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7b9dd9d7 elementor-widget elementor-widget-text-editor\" data-id=\"7b9dd9d7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p style=\"font-size:16px;line-height:1.75;color:#1E293B;margin:0 0 14px 0;\">\u0421\u043e\u043e\u0442\u043d\u043e\u0448\u0435\u043d\u0438\u0435 Firmicutes\/Bacteroidetes (F\/B ratio) \u2014 \u043e\u0434\u0438\u043d \u0438\u0437 \u043a\u043b\u044e\u0447\u0435\u0432\u044b\u0445 \u0438\u043d\u0442\u0435\u0433\u0440\u0430\u043b\u044c\u043d\u044b\u0445 \u043c\u0430\u0440\u043a\u0435\u0440\u043e\u0432 \u0441\u043e\u0441\u0442\u043e\u044f\u043d\u0438\u044f \u043c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u0442\u044b: \u043f\u0440\u0438 \u043e\u0436\u0438\u0440\u0435\u043d\u0438\u0438, \u0421\u0414 2, \u0412\u0417\u041a \u0438 leaky gut \u043e\u043d\u043e, \u043a\u0430\u043a \u043f\u0440\u0430\u0432\u0438\u043b\u043e, \u043d\u0430\u0440\u0443\u0448\u0435\u043d\u043e.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5e6a6f01 elementor-widget elementor-widget-heading\" data-id=\"5e6a6f01\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">\u041a\u0430\u043a \u043c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u043c \u043f\u043e\u0434\u0434\u0435\u0440\u0436\u0438\u0432\u0430\u0435\u0442 \u0431\u0430\u0440\u044c\u0435\u0440 \u2014 5 \u043c\u0435\u0445\u0430\u043d\u0438\u0437\u043c\u043e\u0432<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-678cb0bb elementor-widget elementor-widget-html\" data-id=\"678cb0bb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<div style=\"overflow-x:auto;margin-bottom:20px;\"><table style=\"width:100%;border-collapse:collapse;font-family:Arial,sans-serif;\"><thead><tr><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u041c\u0435\u0445\u0430\u043d\u0438\u0437\u043c<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u041a\u043b\u044e\u0447\u0435\u0432\u044b\u0435 \u0443\u0447\u0430\u0441\u0442\u043d\u0438\u043a\u0438<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u0427\u0442\u043e \u043f\u0440\u043e\u0438\u0437\u0432\u043e\u0434\u0438\u0442\/\u0434\u0435\u043b\u0430\u0435\u0442<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u0421\u0432\u044f\u0437\u044c \u0441 leaky gut<\/th><\/tr><\/thead><tbody><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u041f\u0440\u043e\u0438\u0437\u0432\u043e\u0434\u0441\u0442\u0432\u043e \u041a\u0426\u0416\u041a<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">F. prausnitzii, Roseburia, Bifidobacterium<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0411\u0443\u0442\u0438\u0440\u0430\u0442 (\u043e\u0441\u043d\u043e\u0432\u043d\u043e\u0439), \u043f\u0440\u043e\u043f\u0438\u043e\u043d\u0430\u0442, \u0430\u0446\u0435\u0442\u0430\u0442<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0411\u0443\u0442\u0438\u0440\u0430\u0442 \u2191TJ-\u0433\u0435\u043d\u044b (HDAC-\u0438\u043d\u0433\u0438\u0431.); \u2191PPAR\u03b3; \u043f\u0438\u0442\u0430\u043d\u0438\u0435 \u043a\u043e\u043b\u043e\u043d\u043e\u0446\u0438\u0442\u043e\u0432<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0423\u043a\u0440\u0435\u043f\u043b\u0435\u043d\u0438\u0435 \u0441\u043b\u0438\u0437\u0438\u0441\u0442\u043e\u0433\u043e \u0441\u043b\u043e\u044f<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">Akkermansia muciniphila, Bifidobacterium spp.<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0421\u0442\u0438\u043c\u0443\u043b\u044f\u0446\u0438\u044f \u0441\u0438\u043d\u0442\u0435\u0437\u0430 MUC2 \u0431\u043e\u043a\u0430\u043b\u043e\u0432\u0438\u0434\u043d\u044b\u043c\u0438 \u043a\u043b\u0435\u0442\u043a\u0430\u043c\u0438<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0411\u0435\u0437 \u043c\u0443\u0446\u0438\u043d-\u0441\u043b\u043e\u044f: \u043f\u0440\u044f\u043c\u043e\u0439 \u043a\u043e\u043d\u0442\u0430\u043a\u0442 \u0431\u0430\u043a\u0442\u0435\u0440\u0438\u0439 \u0441 \u044d\u043f\u0438\u0442\u0435\u043b\u0438\u0435\u043c \u2192 \u0432\u043e\u0441\u043f\u0430\u043b\u0435\u043d\u0438\u0435<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0418\u043c\u043c\u0443\u043d\u043d\u0430\u044f \u043c\u043e\u0434\u0443\u043b\u044f\u0446\u0438\u044f<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">Lactobacillus spp., Bacteroides fragilis<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">sIgA, IL-10, TGF-\u03b2 (\u043f\u0440\u043e\u0442\u0438\u0432\u043e\u0432\u043e\u0441\u043f\u0430\u043b\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u0435)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u2193 \u043f\u0440\u043e\u0432\u043e\u0441\u043f\u0430\u043b\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u0445 \u0446\u0438\u0442\u043e\u043a\u0438\u043d\u043e\u0432 \u2192 \u0441\u043e\u0445\u0440\u0430\u043d\u0435\u043d\u0438\u0435 TJ-\u0431\u0435\u043b\u043a\u043e\u0432<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u041a\u043e\u043d\u043a\u0443\u0440\u0435\u043d\u0442\u043d\u043e\u0435 \u0438\u0441\u043a\u043b\u044e\u0447\u0435\u043d\u0438\u0435<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">Lactobacillus spp., Bifidobacterium spp.<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u041a\u043e\u043d\u043a\u0443\u0440\u0435\u043d\u0446\u0438\u044f \u0437\u0430 \u043d\u0438\u0448\u0443 \u0441 \u043f\u0430\u0442\u043e\u0431\u0438\u043e\u043d\u0442\u0430\u043c\u0438<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u041d\u0435 \u0434\u0430\u0451\u0442 \u0440\u0430\u0437\u0432\u0438\u0442\u044c\u0441\u044f E.coli, Klebsiella, C.diff \u2192 \u2193LPS<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0421\u0438\u043d\u0442\u0435\u0437 \u043c\u0435\u0442\u0430\u0431\u043e\u043b\u0438\u0442\u043e\u0432-\u0431\u0430\u0440\u044c\u0435\u0440\u043e\u043f\u0440\u043e\u0442\u0435\u043a\u0442\u043e\u0440\u043e\u0432<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">Faecalibacterium, Bifidobacterium<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0418\u043d\u0434\u043e\u043b, \u043f\u043e\u043b\u0438\u0430\u043c\u0438\u043d\u044b, \u0432\u0442\u043e\u0440\u0438\u0447\u043d\u044b\u0435 \u0436\u0435\u043b\u0447\u043d\u044b\u0435 \u043a\u0438\u0441\u043b\u043e\u0442\u044b<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u2191AhR-\u0441\u0438\u0433\u043d\u0430\u043b\u0438\u043d\u0433 \u2192 \u2191\u043a\u043b\u0430\u0443\u0434\u0438\u043d-5; \u2191TJ-\u044d\u043a\u0441\u043f\u0440\u0435\u0441\u0441\u0438\u044f<\/td><\/tr><\/tbody><\/table><p style=\"font-size:12px;color:#64748B;margin-top:6px;\">180,200,220,230<\/p><\/div>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-309cf360 elementor-widget elementor-widget-text-editor\" data-id=\"309cf360\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div style=\"background:#EFF6FF;border-left:4px solid #1E40AF;border-radius:0 8px 8px 0;padding:16px 20px;margin-bottom:16px;\"><b>\u041a\u043b\u044e\u0447\u0435\u0432\u043e\u0439 \u0444\u0430\u043a\u0442 \u043e \u0431\u0443\u0442\u0438\u0440\u0430\u0442\u0435:<\/b> Faecalibacterium prausnitzii \u2014 \u0433\u043b\u0430\u0432\u043d\u044b\u0439 \u043f\u0440\u043e\u0434\u0443\u0446\u0435\u043d\u0442 \u0431\u0443\u0442\u0438\u0440\u0430\u0442\u0430 \u0432 \u043a\u0438\u0448\u0435\u0447\u043d\u0438\u043a\u0435. \u0415\u0433\u043e \u0441\u043d\u0438\u0436\u0435\u043d\u0438\u0435 <b>\u043d\u0430 50%<\/b> \u043e\u0431\u043d\u0430\u0440\u0443\u0436\u0435\u043d\u043e \u043f\u0440\u0438 \u0431\u043e\u043b\u0435\u0437\u043d\u0438 \u041a\u0440\u043e\u043d\u0430 (Sokol et al., PNAS, 2008) \u0438 \u0443 40\u201360% \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0441 leaky gut-\u0430\u0441\u0441\u043e\u0446\u0438\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u044b\u043c \u0421\u0420\u041a. \u0411\u0443\u0442\u0438\u0440\u0430\u0442 \u2014 \u043d\u0435 \u043f\u0440\u043e\u0441\u0442\u043e \u043f\u0438\u0442\u0430\u043d\u0438\u0435 \u0434\u043b\u044f \u043a\u043b\u0435\u0442\u043a\u0438: \u043e\u043d \u044d\u043f\u0438\u0433\u0435\u043d\u0435\u0442\u0438\u0447\u0435\u0441\u043a\u0438 \u0430\u043a\u0442\u0438\u0432\u0438\u0440\u0443\u0435\u0442 TJ-\u0433\u0435\u043d\u044b \u0447\u0435\u0440\u0435\u0437 \u0438\u043d\u0433\u0438\u0431\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u0435 HDAC.<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-45d8729f elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"45d8729f\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-62778816\" data-id=\"62778816\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-11229828 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"11229828\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-3b2aabbf elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"3b2aabbf\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-2f2f68e0\" data-id=\"2f2f68e0\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-12867f05 elementor-widget elementor-widget-heading\" data-id=\"12867f05\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">2. \u0414\u0438\u0441\u0431\u0438\u043e\u0437 \u043a\u0430\u043a \u043f\u0440\u0438\u0447\u0438\u043d\u0430 \u0434\u044b\u0440\u044f\u0432\u043e\u0433\u043e \u043a\u0438\u0448\u0435\u0447\u043d\u0438\u043a\u0430<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-14e7715a elementor-widget elementor-widget-heading\" data-id=\"14e7715a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">\u0427\u0442\u043e \u0442\u0430\u043a\u043e\u0435 \u0434\u0438\u0441\u0431\u0438\u043e\u0437<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-36f68e53 elementor-widget elementor-widget-text-editor\" data-id=\"36f68e53\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p style=\"font-size:16px;line-height:1.75;color:#1E293B;margin:0 0 14px 0;\">\u0414\u0438\u0441\u0431\u0438\u043e\u0437 \u2014 \u044d\u0442\u043e \u043d\u0435 \u043f\u0440\u043e\u0441\u0442\u043e \u00ab\u043f\u043b\u043e\u0445\u0438\u0435 \u0431\u0430\u043a\u0442\u0435\u0440\u0438\u0438 \u0432\u043c\u0435\u0441\u0442\u043e \u0445\u043e\u0440\u043e\u0448\u0438\u0445\u00bb. \u042d\u0442\u043e \u0441\u0438\u0441\u0442\u0435\u043c\u043d\u043e\u0435 \u043d\u0430\u0440\u0443\u0448\u0435\u043d\u0438\u0435 \u0441\u0442\u0440\u0443\u043a\u0442\u0443\u0440\u044b, \u0444\u0443\u043d\u043a\u0446\u0438\u0438 \u0438 \u043c\u0435\u0442\u0430\u0431\u043e\u043b\u0438\u0447\u0435\u0441\u043a\u043e\u0439 \u0430\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u0438 \u043c\u0438\u043a\u0440\u043e\u0431\u043d\u043e\u0433\u043e \u0441\u043e\u043e\u0431\u0449\u0435\u0441\u0442\u0432\u0430. \u0422\u0440\u0438 \u043a\u043b\u044e\u0447\u0435\u0432\u044b\u0445 \u043a\u043e\u043c\u043f\u043e\u043d\u0435\u043d\u0442\u0430 \u0434\u0438\u0441\u0431\u0438\u043e\u0437\u0430 \u043f\u0440\u0438 leaky gut:<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3d5dd38c elementor-widget elementor-widget-text-editor\" data-id=\"3d5dd38c\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<ol style=\"padding-left:22px;margin:0 0 16px 0;\"><li style=\"font-size:15px;line-height:1.7;color:#1E293B;margin-bottom:8px;\"><b>\u0421\u043d\u0438\u0436\u0435\u043d\u0438\u0435 \u043c\u0438\u043a\u0440\u043e\u0431\u043d\u043e\u0433\u043e \u0440\u0430\u0437\u043d\u043e\u043e\u0431\u0440\u0430\u0437\u0438\u044f (\u03b1-diversity\u2193)<\/b> \u2014 \u0447\u0435\u043c \u043d\u0438\u0436\u0435 \u0440\u0430\u0437\u043d\u043e\u043e\u0431\u0440\u0430\u0437\u0438\u0435, \u0442\u0435\u043c \u0443\u044f\u0437\u0432\u0438\u043c\u0435\u0435 \u0431\u0430\u0440\u044c\u0435\u0440.<\/li><li style=\"font-size:15px;line-height:1.7;color:#1E293B;margin-bottom:8px;\"><b>\u041f\u043e\u0442\u0435\u0440\u044f \u00ab\u043f\u043e\u043b\u0435\u0437\u043d\u044b\u0445\u00bb \u043f\u0440\u043e\u0442\u0435\u043a\u0442\u043e\u0440\u043d\u044b\u0445 \u0432\u0438\u0434\u043e\u0432<\/b> \u2014 \u041a\u0426\u0416\u041a-\u043f\u0440\u043e\u0434\u0443\u0446\u0435\u043d\u0442\u044b \u0438 \u043c\u0443\u0446\u0438\u043d-\u0441\u0438\u043d\u0442\u0435\u0437\u0430\u0442\u043e\u0440\u044b.<\/li><li style=\"font-size:15px;line-height:1.7;color:#1E293B;margin-bottom:8px;\"><b>\u0420\u043e\u0441\u0442 \u00ab\u0432\u0440\u0435\u0434\u043d\u044b\u0445\u00bb \u043f\u0430\u0442\u043e\u0431\u0438\u043e\u043d\u0442\u043e\u0432<\/b> \u2014 LPS-\u043f\u0440\u043e\u0434\u0443\u0446\u0438\u0440\u0443\u044e\u0449\u0438\u0445 \u0433\u0440\u0430\u043c\u043e\u0442\u0440\u0438\u0446\u0430\u0442\u0435\u043b\u044c\u043d\u044b\u0445 \u0431\u0430\u043a\u0442\u0435\u0440\u0438\u0439.<\/li><\/ol>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-62930669 elementor-widget elementor-widget-heading\" data-id=\"62930669\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">\u0411\u0430\u043a\u0442\u0435\u0440\u0438\u0438-\u043f\u0440\u043e\u0442\u0435\u043a\u0442\u043e\u0440\u044b (\u0434\u0435\u0444\u0438\u0446\u0438\u0442 \u043f\u0440\u0438 leaky gut)<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-31147b41 elementor-widget elementor-widget-html\" data-id=\"31147b41\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<div style=\"overflow-x:auto;margin-bottom:20px;\"><table style=\"width:100%;border-collapse:collapse;font-family:Arial,sans-serif;\"><thead><tr><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u0411\u0430\u043a\u0442\u0435\u0440\u0438\u044f<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u0417\u0430\u0449\u0438\u0442\u043d\u0430\u044f \u0440\u043e\u043b\u044c<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u0427\u0442\u043e \u043f\u0440\u043e\u0438\u0441\u0445\u043e\u0434\u0438\u0442 \u043f\u0440\u0438 \u0434\u0435\u0444\u0438\u0446\u0438\u0442\u0435<\/th><\/tr><\/thead><tbody><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">Faecalibacterium prausnitzii<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0413\u043b\u0430\u0432\u043d\u044b\u0439 \u043f\u0440\u043e\u0434\u0443\u0446\u0435\u043d\u0442 \u0431\u0443\u0442\u0438\u0440\u0430\u0442\u0430; \u2191TJ; \u2193TNF-\u03b1, IL-6, IL-12<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u2193 \u0431\u0430\u0440\u044c\u0435\u0440\u043d\u0430\u044f \u0444\u0443\u043d\u043a\u0446\u0438\u044f; \u2191\u0432\u043e\u0441\u043f\u0430\u043b\u0435\u043d\u0438\u0435; \u043f\u0440\u0435\u0434\u0438\u043a\u0442\u043e\u0440 \u0440\u0435\u0446\u0438\u0434\u0438\u0432\u0430 \u0412\u0417\u041a<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">Akkermansia muciniphila<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0423\u043a\u0440\u0435\u043f\u043b\u044f\u0435\u0442 \u0441\u043b\u043e\u0439 \u043c\u0443\u0446\u0438\u043d\u0430; \u2191TJ; \u2191GLP-1; \u043c\u0435\u0442\u0430\u0431\u043e\u043b\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u0437\u0430\u0449\u0438\u0442\u0430<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0418\u0441\u0442\u043e\u043d\u0447\u0435\u043d\u0438\u0435 \u0441\u043b\u0438\u0437\u0438\u0441\u0442\u043e\u0433\u043e \u0441\u043b\u043e\u044f \u2192 \u0431\u0430\u043a\u0442\u0435\u0440\u0438\u0430\u043b\u044c\u043d\u0430\u044f \u0442\u0440\u0430\u043d\u0441\u043b\u043e\u043a\u0430\u0446\u0438\u044f<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">Roseburia intestinalis<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0413\u043b\u0430\u0432\u043d\u044b\u0439 \u043f\u0440\u043e\u0434\u0443\u0446\u0435\u043d\u0442 \u0431\u0443\u0442\u0438\u0440\u0430\u0442\u0430 \u0432 \u0432\u043e\u0441\u0445\u043e\u0434\u044f\u0449\u0435\u0439 \u043e\u0431\u043e\u0434\u043e\u0447\u043d\u043e\u0439 \u043a\u0438\u0448\u043a\u0435<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u2193\u041a\u0426\u0416\u041a \u2192 \u0441\u043d\u0438\u0436\u0435\u043d\u0438\u0435 TJ-\u044d\u043a\u0441\u043f\u0440\u0435\u0441\u0441\u0438\u0438<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">Bifidobacterium longum<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u2191sIgA; \u2193IL-8; \u2191\u0430\u0446\u0435\u0442\u0430\u0442; \u043a\u043e\u043d\u043a\u0443\u0440\u0435\u043d\u0442\u043d\u043e\u0435 \u0438\u0441\u043a\u043b\u044e\u0447\u0435\u043d\u0438\u0435 \u043f\u0430\u0442\u043e\u0433\u0435\u043d\u043e\u0432<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0420\u043e\u0441\u0442 E.coli \u0438 Klebsiella \u2192 \u2191LPS \u2192 \u0432\u043e\u0441\u043f\u0430\u043b\u0435\u043d\u0438\u0435<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">Lactobacillus reuteri<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0421\u0438\u043d\u0442\u0435\u0437 \u0440\u0435\u0443\u0442\u0435\u0440\u0438\u043d\u0430 (\u0430\u043d\u0442\u0438\u043c\u0438\u043a\u0440\u043e\u0431\u043d\u044b\u0439); \u2191TJ; \u2191IL-10<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u041d\u0430\u0440\u0443\u0448\u0435\u043d\u0438\u0435 \u043b\u043e\u043a\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u0438\u043c\u043c\u0443\u043d\u043d\u043e\u0433\u043e \u0433\u043e\u043c\u0435\u043e\u0441\u0442\u0430\u0437\u0430<\/td><\/tr><\/tbody><\/table><p style=\"font-size:12px;color:#64748B;margin-top:6px;\">200,240,250<\/p><\/div>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3d1d759f elementor-widget elementor-widget-heading\" data-id=\"3d1d759f\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">LPS-\u043f\u0440\u043e\u0434\u0443\u0446\u0438\u0440\u0443\u044e\u0449\u0438\u0435 \u0431\u0430\u043a\u0442\u0435\u0440\u0438\u0438 \u2014 \u0442\u0440\u0438\u0433\u0433\u0435\u0440\u044b \u0432\u043e\u0441\u043f\u0430\u043b\u0435\u043d\u0438\u044f<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-35b5258b elementor-widget elementor-widget-text-editor\" data-id=\"35b5258b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p style=\"font-size:16px;line-height:1.75;color:#1E293B;margin:0 0 14px 0;\">\u041b\u041f\u0421 (\u043b\u0438\u043f\u043e\u043f\u043e\u043b\u0438\u0441\u0430\u0445\u0430\u0440\u0438\u0434) \u2014 \u043a\u043e\u043c\u043f\u043e\u043d\u0435\u043d\u0442 \u043a\u043b\u0435\u0442\u043e\u0447\u043d\u043e\u0439 \u0441\u0442\u0435\u043d\u043a\u0438 \u0433\u0440\u0430\u043c\u043e\u0442\u0440\u0438\u0446\u0430\u0442\u0435\u043b\u044c\u043d\u044b\u0445 \u0431\u0430\u043a\u0442\u0435\u0440\u0438\u0439. \u041f\u0440\u0438 \u0434\u0438\u0441\u0431\u0438\u043e\u0437\u0435 \u0440\u043e\u0441\u0442 \u0433\u0440\u0430\u043c\u043e\u0442\u0440\u0438\u0446\u0430\u0442\u0435\u043b\u044c\u043d\u044b\u0445 \u0432\u0438\u0434\u043e\u0432 + \u043f\u043e\u0432\u044b\u0448\u0435\u043d\u043d\u0430\u044f \u041f\u041a\u041f \u2192 <b>\u043c\u0435\u0442\u0430\u0431\u043e\u043b\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u044d\u043d\u0434\u043e\u0442\u043e\u043a\u0441\u0435\u043c\u0438\u044f<\/b> (Cani et al., Diabetes, 2007):<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-20ae915b elementor-widget elementor-widget-text-editor\" data-id=\"20ae915b\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<ul style=\"padding-left:22px;margin:0 0 16px 0;\"><li style=\"font-size:15px;line-height:1.7;color:#1E293B;margin-bottom:7px;\"><b>\u041b\u041f\u0421 \u2192 TLR4-\u0440\u0435\u0446\u0435\u043f\u0442\u043e\u0440\u044b<\/b> \u043d\u0430 \u044d\u043f\u0438\u0442\u0435\u043b\u0438\u043e\u0446\u0438\u0442\u0430\u0445, \u043c\u0430\u043a\u0440\u043e\u0444\u0430\u0433\u0430\u0445, \u0430\u0434\u0438\u043f\u043e\u0446\u0438\u0442\u0430\u0445 \u2192 NF-\u03baB \u2192 \u043f\u0440\u043e\u0432\u043e\u0441\u043f\u0430\u043b\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u0435 \u0446\u0438\u0442\u043e\u043a\u0438\u043d\u044b (TNF-\u03b1, IL-1\u03b2, IL-6).<\/li><li style=\"font-size:15px;line-height:1.7;color:#1E293B;margin-bottom:7px;\"><b>TNF-\u03b1 \u0438 IL-1\u03b2<\/b> \u2192 \u043d\u0430\u0440\u0443\u0448\u0435\u043d\u0438\u0435 ZO-1, \u043e\u043a\u043a\u043b\u044e\u0434\u0438\u043d\u0430 \u2192 \u043e\u0442\u043a\u0440\u044b\u0442\u0438\u0435 TJ \u2192 \u0435\u0449\u0451 \u0431\u043e\u043b\u044c\u0448\u0435 \u041b\u041f\u0421 \u2192 \u043f\u043e\u0440\u043e\u0447\u043d\u044b\u0439 \u043a\u0440\u0443\u0433.<\/li><li style=\"font-size:15px;line-height:1.7;color:#1E293B;margin-bottom:7px;\"><b>LBP (\u041b\u041f\u0421-\u0441\u0432\u044f\u0437\u044b\u0432\u0430\u044e\u0449\u0438\u0439 \u0431\u0435\u043b\u043e\u043a) \u0432 \u043f\u043b\u0430\u0437\u043c\u0435<\/b> >5.8 \u043c\u043a\u0433\/\u043c\u043b \u2014 \u043c\u0430\u0440\u043a\u0435\u0440 \u0445\u0440\u043e\u043d\u0438\u0447\u0435\u0441\u043a\u043e\u0439 \u044d\u043d\u0434\u043e\u0442\u043e\u043a\u0441\u0435\u043c\u0438\u0438; \u043a\u043e\u0440\u0440\u0435\u043b\u0438\u0440\u0443\u0435\u0442 \u0441 \u043e\u0436\u0438\u0440\u0435\u043d\u0438\u0435\u043c, \u041d\u0410\u0416\u0411\u041f, \u0438\u043d\u0441\u0443\u043b\u0438\u043d\u043e\u0440\u0435\u0437\u0438\u0441\u0442\u0435\u043d\u0442\u043d\u043e\u0441\u0442\u044c\u044e.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1a0107b3 elementor-widget elementor-widget-heading\" data-id=\"1a0107b3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">\u041a\u043b\u044e\u0447\u0435\u0432\u044b\u0435 \u043c\u0435\u0445\u0430\u043d\u0438\u0437\u043c\u044b: \u0434\u0438\u0441\u0431\u0438\u043e\u0437 \u2192 leaky gut<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6b0c1dd1 elementor-widget elementor-widget-html\" data-id=\"6b0c1dd1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<div style=\"overflow-x:auto;margin-bottom:20px;\"><table style=\"width:100%;border-collapse:collapse;font-family:Arial,sans-serif;\"><thead><tr><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u041f\u0430\u0442\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u043e\u0435 \u0437\u0432\u0435\u043d\u043e<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u041c\u0435\u0445\u0430\u043d\u0438\u0437\u043c<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u041a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u043e\u0435 \u0441\u043b\u0435\u0434\u0441\u0442\u0432\u0438\u0435<\/th><\/tr><\/thead><tbody><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u2193\u041a\u0426\u0416\u041a (\u2193F.prausnitzii, \u2193Roseburia)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u041d\u0435\u0442 HDAC-\u0438\u043d\u0433\u0438\u0431\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u044f \u2192 \u0441\u043d\u0438\u0436\u0435\u043d\u0438\u0435 TJ-\u0433\u0435\u043d\u043e\u0432 (ZO-1, \u043a\u043b\u0430\u0443\u0434\u0438\u043d)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u041c\u0435\u0434\u043b\u0435\u043d\u043d\u0430\u044f \u00ab\u0443\u0442\u0435\u0447\u043a\u0430\u00bb \u0431\u0430\u0440\u044c\u0435\u0440\u0430; \u0445\u0440. \u0443\u0441\u0442\u0430\u043b\u043e\u0441\u0442\u044c, \u0432\u0437\u0434\u0443\u0442\u0438\u0435<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u2193Akkermansia muciniphila<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0418\u0441\u0442\u043e\u043d\u0447\u0435\u043d\u0438\u0435 \u0441\u043b\u043e\u044f \u043c\u0443\u0446\u0438\u043d\u0430 MUC2 \u2192 \u043f\u0440\u044f\u043c\u043e\u0439 \u043a\u043e\u043d\u0442\u0430\u043a\u0442 \u0431\u0430\u043a\u0442\u0435\u0440\u0438\u0439 \u0441 \u044d\u043f\u0438\u0442\u0435\u043b\u0438\u0435\u043c<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u041b\u043e\u043a\u0430\u043b\u044c\u043d\u043e\u0435 \u0432\u043e\u0441\u043f\u0430\u043b\u0435\u043d\u0438\u0435 \u0441\u043b\u0438\u0437\u0438\u0441\u0442\u043e\u0439 \u2192 \u0437\u043e\u043d\u0443\u043b\u0438\u043d\u2191<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u2191E.coli, \u2191Klebsiella, \u2191Prevotella<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">LPS-\u043f\u0435\u0440\u0435\u0433\u0440\u0443\u0437\u043a\u0430 \u2192 TLR4 \u2192 NF-\u03baB \u2192 TNF-\u03b1\/IL-1\u03b2<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u041f\u041a\u041f + \u0441\u0438\u0441\u0442\u0435\u043c\u043d\u043e\u0435 \u0432\u043e\u0441\u043f\u0430\u043b\u0435\u043d\u0438\u0435 + \u0438\u043d\u0441\u0443\u043b\u0438\u043d\u043e\u0440\u0435\u0437\u0438\u0441\u0442\u0435\u043d\u0442\u043d\u043e\u0441\u0442\u044c<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0421\u0418\u0411\u041e (\u043a\u0438\u0448\u0435\u0447\u043d\u0438\u043a)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">D-\u043b\u0430\u043a\u0442\u0430\u0442 + LPS \u0432 \u0442\u043e\u043d\u043a\u043e\u0439 \u043a\u0438\u0448\u043a\u0435 + \u043f\u043e\u0432\u0440\u0435\u0436\u0434\u0435\u043d\u0438\u0435 \u0432\u043e\u0440\u0441\u0438\u043d\u043e\u043a<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0412\u0437\u0434\u0443\u0442\u0438\u0435, brain fog, \u0445\u0440\u043e\u043d\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u0443\u0441\u0442\u0430\u043b\u043e\u0441\u0442\u044c, \u0437\u043e\u043d\u0443\u043b\u0438\u043d\u2191\u2191<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">Candida albicans (\u043e\u0432\u0435\u0440\u0433\u0440\u043e\u0441\u0442)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0413\u0438\u0444\u044b \u2192 \u043c\u0435\u0445\u0430\u043d\u0438\u0447\u0435\u0441\u043a\u043e\u0435 \u043f\u0440\u043e\u043d\u0438\u043a\u043d\u043e\u0432\u0435\u043d\u0438\u0435 \u0447\u0435\u0440\u0435\u0437 TJ; \u043f\u0440\u043e\u0442\u0435\u0430\u0437\u044b Sap1-6<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u041a\u0430\u043d\u0434\u0438\u0434\u043e\u0437 + \u041f\u041a\u041f; \u0430\u043a\u043d\u0435, \u043a\u043e\u0436\u043d\u044b\u0435 \u043f\u0440\u043e\u044f\u0432\u043b\u0435\u043d\u0438\u044f<\/td><\/tr><\/tbody><\/table><p style=\"font-size:12px;color:#64748B;margin-top:6px;\">200,230,250<\/p><\/div>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1352f673 elementor-widget elementor-widget-text-editor\" data-id=\"1352f673\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div style=\"background: #F0F9FF; border: 1px solid #BAE6FD; border-radius: 8px; padding: 12px 18px; margin-bottom: 10px;\"><p><span style=\"color: #0284c7; font-size: 15px; font-weight: 600;\">\u2192 <\/span><a style=\"color: #0284c7; font-size: 15px; font-weight: 600; text-decoration: none;\" href=\"https:\/\/novolakrb1.ru\/statii\/zonulin-analiz-normy\/\">\u0417\u043e\u043d\u0443\u043b\u0438\u043d \u2014 \u0431\u0438\u043e\u043c\u0430\u0440\u043a\u0435\u0440 \u0434\u0438\u0441\u0431\u0438\u043e\u0437-\u0437\u0430\u0432\u0438\u0441\u0438\u043c\u043e\u0439 \u041f\u041a\u041f: \u0430\u043d\u0430\u043b\u0438\u0437, \u043d\u043e\u0440\u043c\u044b, \u043a\u0430\u043a \u0441\u043d\u0438\u0437\u0438\u0442\u044c<\/a><\/p><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-516fdda2 elementor-widget elementor-widget-text-editor\" data-id=\"516fdda2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div style=\"background: #F0F9FF; border: 1px solid #BAE6FD; border-radius: 8px; padding: 12px 18px; margin-bottom: 10px;\"><p><span style=\"color: #0284c7; font-size: 15px; font-weight: 600;\">\u2192 <\/span><a style=\"color: #0284c7; font-size: 15px; font-weight: 600; text-decoration: none;\" href=\"https:\/\/novolakrb1.ru\/statii\/tight-junctions-kishechnik\/\">\u041c\u043e\u043b\u0435\u043a\u0443\u043b\u044f\u0440\u043d\u044b\u0439 \u0440\u0430\u0437\u0431\u043e\u0440 TJ-\u0431\u0435\u043b\u043a\u043e\u0432: \u0447\u0442\u043e \u0440\u0430\u0437\u0440\u0443\u0448\u0430\u0435\u0442 ZO-1, \u043e\u043a\u043a\u043b\u044e\u0434\u0438\u043d, \u043a\u043b\u0430\u0443\u0434\u0438\u043d\u044b \u0438 \u043a\u0430\u043a \u0438\u0445 \u0432\u043e\u0441\u0441\u0442\u0430\u043d\u043e\u0432\u0438\u0442\u044c<\/a><\/p><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-35f7d725 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"35f7d725\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-6ba3a10c\" data-id=\"6ba3a10c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-6c19f5d1 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"6c19f5d1\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-226a1dfa elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"226a1dfa\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-46659c95\" data-id=\"46659c95\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-770c7ca2 elementor-widget elementor-widget-heading\" data-id=\"770c7ca2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">3. \u0422\u0435\u0441\u0442\u044b \u043c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u043c\u0430 \u0432 \u0420\u0424 2026: \u0441\u0440\u0430\u0432\u043d\u0435\u043d\u0438\u0435, \u0447\u0442\u043e \u0432\u044b\u0431\u0440\u0430\u0442\u044c, \u043a\u0430\u043a \u0438\u043d\u0442\u0435\u0440\u043f\u0440\u0435\u0442\u0438\u0440\u043e\u0432\u0430\u0442\u044c<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-114af7e9 elementor-widget elementor-widget-heading\" data-id=\"114af7e9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">\u0422\u0438\u043f\u044b \u0442\u0435\u0441\u0442\u043e\u0432 \u0438 \u0442\u0435\u0445\u043d\u043e\u043b\u043e\u0433\u0438\u0438<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-a7f2025 elementor-widget elementor-widget-html\" data-id=\"a7f2025\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<div style=\"overflow-x:auto;margin-bottom:20px;\"><table style=\"width:100%;border-collapse:collapse;font-family:Arial,sans-serif;\"><thead><tr><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u0422\u0435\u0445\u043d\u043e\u043b\u043e\u0433\u0438\u044f<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u0427\u0442\u043e \u043e\u043f\u0440\u0435\u0434\u0435\u043b\u044f\u0435\u0442<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u0422\u043e\u0447\u043d\u043e\u0441\u0442\u044c<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u0414\u043b\u044f \u043a\u043e\u0433\u043e<\/th><\/tr><\/thead><tbody><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">16S rRNA \u0430\u043c\u043f\u043b\u0438\u043a\u043e\u043d\u043d\u043e\u0435 \u0441\u0435\u043a\u0432\u0435\u043d\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u0435<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0411\u0430\u043a\u0442\u0435\u0440\u0438\u0430\u043b\u044c\u043d\u044b\u0439 \u0441\u043e\u0441\u0442\u0430\u0432 (\u0434\u043e \u0440\u043e\u0434\u0430\/\u0432\u0438\u0434\u0430)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0423\u043c\u0435\u0440\u0435\u043d\u043d\u0430\u044f (\u043e\u0448\u0438\u0431\u043a\u0430 \u043d\u0430 \u0443\u0440\u043e\u0432\u043d\u0435 \u0432\u0438\u0434\u043e\u0432 ~15%)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0421\u043a\u0440\u0438\u043d\u0438\u043d\u0433 \u0434\u0438\u0441\u0431\u0438\u043e\u0437\u0430; \u0431\u0430\u0437\u043e\u0432\u0430\u044f \u043e\u0446\u0435\u043d\u043a\u0430 F\/B ratio, \u041a\u0426\u0416\u041a-\u043f\u0440\u043e\u0434\u0443\u0446\u0435\u043d\u0442\u043e\u0432<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u041c\u0435\u0442\u0430\u0433\u0435\u043d\u043e\u043c\u043d\u043e\u0435 \u0441\u0435\u043a\u0432\u0435\u043d\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u0435 (WGS)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u041f\u043e\u043b\u043d\u044b\u0439 \u0433\u0435\u043d\u043e\u043c \u043c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u0442\u044b + \u0444\u0443\u043d\u043a\u0446\u0438\u0438 + \u0440\u0435\u0437\u0438\u0441\u0442\u0435\u043d\u0442\u043d\u043e\u0441\u0442\u044c<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0412\u044b\u0441\u043e\u043a\u0430\u044f (\u0434\u043e \u0448\u0442\u0430\u043c\u043c\u0430)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0418\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u0442\u0435\u043b\u044c\u0441\u043a\u0438\u0439 \u0441\u0442\u0430\u043d\u0434\u0430\u0440\u0442; \u043f\u0435\u0440\u0441\u043e\u043d\u0430\u043b\u0438\u0437\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u044b\u0435 \u043f\u0440\u043e\u0442\u043e\u043a\u043e\u043b\u044b (\u0434\u043e\u0440\u043e\u0433\u043e\u0441\u0442\u043e\u044f\u0449\u0438\u0439)<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u041c\u0435\u0442\u0430\u0431\u043e\u043b\u043e\u043c\u0438\u043a\u0430 (\u043a\u0430\u043b\/\u043c\u043e\u0447\u0430)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u041c\u0435\u0442\u0430\u0431\u043e\u043b\u0438\u0442\u044b: \u041a\u0426\u0416\u041a, \u0438\u043d\u0434\u043e\u043b\u044b, \u0436\u0435\u043b\u0447\u043d\u044b\u0435 \u043a\u0438\u0441\u043b\u043e\u0442\u044b<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0424\u0443\u043d\u043a\u0446\u0438\u043e\u043d\u0430\u043b\u044c\u043d\u0430\u044f \u043e\u0446\u0435\u043d\u043a\u0430<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u041a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u0446\u0435\u043d\u0442\u0440\u044b; \u0434\u043e\u043f\u043e\u043b\u043d\u044f\u0435\u0442 16S<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u041a\u0443\u043b\u044c\u0442\u0443\u0440\u0430\u043b\u044c\u043d\u044b\u0439 \u043c\u0435\u0442\u043e\u0434 (\u043f\u043e\u0441\u0435\u0432)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0420\u043e\u0441\u0442 \u043a\u043e\u043d\u043a\u0440\u0435\u0442\u043d\u044b\u0445 \u043f\u0430\u0442\u043e\u0433\u0435\u043d\u043e\u0432; \u0447\u0443\u0432\u0441\u0442\u0432\u0438\u0442. \u043a \u0430\u043d\u0442\u0438\u0431\u0438\u043e\u0442\u0438\u043a\u0430\u043c<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0412\u044b\u0441\u043e\u043a\u0430\u044f \u0434\u043b\u044f \u043f\u0430\u0442\u043e\u0433\u0435\u043d\u043e\u0432; \u043d\u0435 \u0432\u0438\u0434\u0438\u0442 \u0430\u043d\u0430\u044d\u0440\u043e\u0431\u044b<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u041f\u0440\u0438 \u043f\u043e\u0434\u043e\u0437\u0440\u0435\u043d\u0438\u0438 \u043d\u0430 \u0421\u0418\u0411\u041e, C.diff, Candida<\/td><\/tr><\/tbody><\/table><p style=\"font-size:12px;color:#64748B;margin-top:6px;\">230,200,160,230<\/p><\/div>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1af88a80 elementor-widget elementor-widget-heading\" data-id=\"1af88a80\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">\u0421\u0440\u0430\u0432\u043d\u0435\u043d\u0438\u0435 \u043a\u043e\u043c\u043c\u0435\u0440\u0447\u0435\u0441\u043a\u0438\u0445 \u0442\u0435\u0441\u0442\u043e\u0432 \u043c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u043c\u0430 \u0432 \u0420\u0424 2026<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7a63ca26 elementor-widget elementor-widget-html\" data-id=\"7a63ca26\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<div style=\"overflow-x:auto;margin-bottom:20px;\"><table style=\"width:100%;border-collapse:collapse;font-family:Arial,sans-serif;\"><thead><tr><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u0421\u0435\u0440\u0432\u0438\u0441<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u0422\u0435\u0445\u043d\u043e\u043b\u043e\u0433\u0438\u044f<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u0427\u0442\u043e \u0432\u043a\u043b\u044e\u0447\u0435\u043d\u043e<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u0426\u0435\u043d\u0430<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u0414\u043e\u0441\u0442\u0443\u043f\u043d\u043e\u0441\u0442\u044c<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u041e\u0446\u0435\u043d\u043a\u0430<\/th><\/tr><\/thead><tbody><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">Atlas Biomed<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">16S rRNA<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0421\u043e\u0441\u0442\u0430\u0432 \u043c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u0442\u044b + \u0440\u0435\u043a\u043e\u043c\u0435\u043d\u0434\u0430\u0446\u0438\u0438 \u043f\u043e \u043f\u0438\u0442\u0430\u043d\u0438\u044e + \u041a\u0426\u0416\u041a-\u043f\u0440\u043e\u0444\u0438\u043b\u044c<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">5 990\u20139 990 \u0440.<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0412\u0441\u044f \u0420\u0424 (\u043f\u043e\u0447\u0442\u0430)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u2b50\u2b50\u2b50\u2b50 \u041b\u0443\u0447\u0448\u0438\u0439 \u0434\u043b\u044f \u043f\u043e\u0442\u0440\u0435\u0431\u0438\u0442\u0435\u043b\u044f<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">Genetico<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">16S rRNA \/ WGS (\u043f\u043e \u0442\u0430\u0440\u0438\u0444\u0443)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0413\u043b\u0443\u0431\u043e\u043a\u0438\u0439 \u0442\u0430\u043a\u0441\u043e\u043d\u043e\u043c\u0438\u0447\u0435\u0441\u043a\u0438\u0439 \u0430\u043d\u0430\u043b\u0438\u0437; \u043e\u043f\u0446\u0438\u044f WGS<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">8 000\u201325 000 \u0440.<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u041c\u043e\u0441\u043a\u0432\u0430 + \u043f\u0430\u0440\u0442\u043d\u0451\u0440\u044b<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u2b50\u2b50\u2b50\u2b50\u2b50 \u041c\u0430\u043a\u0441\u0438\u043c\u0430\u043b\u044c\u043d\u0430\u044f \u0433\u043b\u0443\u0431\u0438\u043d\u0430<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">InVivo Diagnostics<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">16S rRNA + LPS + \u0437\u043e\u043d\u0443\u043b\u0438\u043d<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0411\u0430\u0440\u044c\u0435\u0440-\u043e\u0440\u0438\u0435\u043d\u0442\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u044b\u0439: \u0437\u043e\u043d\u0443\u043b\u0438\u043d + LPS + \u043c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u043c<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">12 000\u201318 000 \u0440.<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0427\u0435\u0440\u0435\u0437 \u043a\u043b\u0438\u043d\u0438\u043a\u0438-\u043f\u0430\u0440\u0442\u043d\u0451\u0440\u044b<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u2b50\u2b50\u2b50\u2b50\u2b50 \u041b\u0443\u0447\u0448\u0438\u0439 \u043f\u0440\u0438 leaky gut<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">Helix (\u0414\u041d\u041a-\u0422\u0435\u0445\u043d\u043e\u043b\u043e\u0433\u0438\u044f)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">16S rRNA<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0411\u0430\u0437\u043e\u0432\u044b\u0439 \u0441\u043e\u0441\u0442\u0430\u0432 + \u043d\u0443\u0442\u0440\u0438\u0446\u0438\u043e\u043b\u043e\u0433\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u0440\u0435\u043a\u043e\u043c\u0435\u043d\u0434\u0430\u0446\u0438\u0438<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">4 500\u20137 500 \u0440.<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0412\u0441\u044f \u0420\u0424<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u2b50\u2b50\u2b50 \u0414\u043e\u0441\u0442\u0443\u043f\u043d\u044b\u0439 \u0441\u043a\u0440\u0438\u043d\u0438\u043d\u0433<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0427\u0435\u043a-\u0410\u043f.\u0440\u0443<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">16S rRNA<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0421\u043a\u0440\u0438\u043d\u0438\u043d\u0433 + PDF-\u043e\u0442\u0447\u0451\u0442<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">3 900\u20135 500 \u0440.<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u041c\u043e\u0441\u043a\u0432\u0430, \u043e\u043d\u043b\u0430\u0439\u043d-\u043e\u0442\u043f\u0440\u0430\u0432\u043a\u0430<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u2b50\u2b50\u2b50 \u0411\u0430\u0437\u043e\u0432\u044b\u0439 \u0443\u0440\u043e\u0432\u0435\u043d\u044c<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u041f\u0435\u0440\u0441\u043e\u043d\u0430\u043b\u0438\u0437\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u0430\u044f FMT-\u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u0430<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u041c\u0435\u0442\u0430\u0433\u0435\u043d\u043e\u043c\u0438\u043a\u0430 WGS<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0412 \u0440\u0430\u043c\u043a\u0430\u0445 FMT-\u043f\u0440\u043e\u0442\u043e\u043a\u043e\u043b\u0430 (\u0431\u0430\u043d\u043a\u0438 \u0444\u0435\u043a\u0430\u043b\u044c\u043d\u043e\u0439 \u043c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u0442\u044b)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u041f\u043e \u043f\u0440\u043e\u0442\u043e\u043a\u043e\u043b\u0443 \u043a\u043b\u0438\u043d\u0438\u043a\u0438<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u041c\u043e\u0441\u043a\u0432\u0430, \u0421\u041f\u0431 (2026: \u043d\u043e\u0432\u044b\u0435 FMT-\u0431\u0430\u043d\u043a\u0438)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u2b50\u2b50\u2b50\u2b50\u2b50 \u041a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u0433\u043b\u0443\u0431\u0438\u043d\u0430<\/td><\/tr><\/tbody><\/table><p style=\"font-size:12px;color:#64748B;margin-top:6px;\">140,140,210,100,150,150<\/p><\/div>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-214749f6 elementor-widget elementor-widget-heading\" data-id=\"214749f6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">\u041a\u0430\u043a \u043f\u0440\u0430\u0432\u0438\u043b\u044c\u043d\u043e \u0438\u043d\u0442\u0435\u0440\u043f\u0440\u0435\u0442\u0438\u0440\u043e\u0432\u0430\u0442\u044c \u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442 \u0442\u0435\u0441\u0442\u0430 \u043c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u043c\u0430<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-33788bc2 elementor-widget elementor-widget-text-editor\" data-id=\"33788bc2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div style=\"background:#FFFBEB;border-left:4px solid #D97706;border-radius:0 8px 8px 0;padding:16px 20px;margin-bottom:16px;\"><b>\u041a\u0440\u0438\u0442\u0438\u0447\u0435\u0441\u043a\u043e\u0435 \u043f\u0440\u0435\u0434\u0443\u043f\u0440\u0435\u0436\u0434\u0435\u043d\u0438\u0435 (Scientific American, 2026; Communications Biology, 2026):<\/b><br>\n    \u0414\u043e\u043c\u0430\u0448\u043d\u0438\u0435 \u0442\u0435\u0441\u0442\u044b \u043c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u043c\u0430 \u043f\u043e\u043a\u0430\u0437\u044b\u0432\u0430\u044e\u0442 <b>\u0432\u044b\u0441\u043e\u043a\u0443\u044e \u0432\u0430\u0440\u0438\u0430\u0431\u0435\u043b\u044c\u043d\u043e\u0441\u0442\u044c<\/b> \u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u043e\u0432: \u043f\u043e\u0432\u0442\u043e\u0440\u043d\u044b\u0439 \u0442\u0435\u0441\u0442 \u0442\u043e\u0433\u043e \u0436\u0435 \u043e\u0431\u0440\u0430\u0437\u0446\u0430 \u0432 \u0440\u0430\u0437\u043d\u044b\u0445 \u043b\u0430\u0431\u043e\u0440\u0430\u0442\u043e\u0440\u0438\u044f\u0445 \u043c\u043e\u0436\u0435\u0442 \u0434\u0430\u0432\u0430\u0442\u044c \u0440\u0430\u0437\u043d\u044b\u0435 \u00ab\u0434\u0438\u0430\u0433\u043d\u043e\u0437\u044b\u00bb. \u042d\u0442\u043e \u043d\u0435 \u043e\u0437\u043d\u0430\u0447\u0430\u0435\u0442, \u0447\u0442\u043e \u0442\u0435\u0441\u0442\u044b \u0431\u0435\u0441\u043f\u043e\u043b\u0435\u0437\u043d\u044b \u2014 \u043e\u043d\u0438 \u0445\u043e\u0440\u043e\u0448\u0438 \u0434\u043b\u044f <b>\u0442\u0440\u0435\u043d\u0434\u043e\u0432<\/b> (\u0435\u0441\u0442\u044c\/\u043d\u0435\u0442 \u0434\u0438\u0441\u0431\u0438\u043e\u0437, \u0435\u0441\u0442\u044c\/\u043d\u0435\u0442 \u041a\u0426\u0416\u041a-\u0434\u0435\u0444\u0438\u0446\u0438\u0442), \u043d\u043e \u043d\u0435 \u0434\u043b\u044f \u0442\u043e\u0447\u043d\u043e\u0439 \u043d\u0443\u043c\u0435\u0440\u043e\u043b\u043e\u0433\u0438\u0438.<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-14184e97 elementor-widget elementor-widget-text-editor\" data-id=\"14184e97\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<ul style=\"padding-left:22px;margin:0 0 16px 0;\"><li style=\"font-size:15px;line-height:1.7;color:#1E293B;margin-bottom:7px;\"><b>\u0421\u043c\u043e\u0442\u0440\u0438\u0442\u0435 \u043d\u0430 \u043a\u043b\u044e\u0447\u0435\u0432\u044b\u0435 \u043c\u0430\u0440\u043a\u0435\u0440\u044b:<\/b> F. prausnitzii (>5% \u2014 \u0445\u043e\u0440\u043e\u0448\u043e), Akkermansia muciniphila (>1% \u2014 \u0445\u043e\u0440\u043e\u0448\u043e), \u0440\u0430\u0437\u043d\u043e\u043e\u0431\u0440\u0430\u0437\u0438\u0435 (Shannon index >3.5 \u2014 \u0445\u043e\u0440\u043e\u0448\u043e), F\/B ratio (\u043d\u043e\u0440\u043c\u0430: 1.5\u20133).<\/li><li style=\"font-size:15px;line-height:1.7;color:#1E293B;margin-bottom:7px;\"><b>\u041d\u0435 \u0430\u0431\u0441\u043e\u043b\u044e\u0442\u0438\u0437\u0438\u0440\u0443\u0439\u0442\u0435 \u043f\u0440\u043e\u0446\u0435\u043d\u0442\u044b \u043a\u043e\u043d\u043a\u0440\u0435\u0442\u043d\u044b\u0445 \u0432\u0438\u0434\u043e\u0432<\/b> \u2014 \u0432\u0430\u0440\u0438\u0430\u0431\u0435\u043b\u044c\u043d\u043e\u0441\u0442\u044c \u043c\u0435\u0436\u0434\u0443 \u043e\u0431\u0440\u0430\u0437\u0446\u0430\u043c\u0438 \u043e\u0434\u043d\u043e\u0433\u043e \u0447\u0435\u043b\u043e\u0432\u0435\u043a\u0430 \u0432 \u0440\u0430\u0437\u043d\u044b\u0435 \u0434\u043d\u0438 \u0434\u043e\u0441\u0442\u0438\u0433\u0430\u0435\u0442 40\u201360%.<\/li><li style=\"font-size:15px;line-height:1.7;color:#1E293B;margin-bottom:7px;\"><b>\u0424\u0443\u043d\u043a\u0446\u0438\u043e\u043d\u0430\u043b\u044c\u043d\u044b\u0435 \u043c\u0430\u0440\u043a\u0435\u0440\u044b \u0432\u0430\u0436\u043d\u0435\u0435 \u0442\u0430\u043a\u0441\u043e\u043d\u043e\u043c\u0438\u0438<\/b>: \u0443\u0440\u043e\u0432\u0435\u043d\u044c \u041a\u0426\u0416\u041a (\u0431\u0443\u0442\u0438\u0440\u0430\u0442, \u043f\u0440\u043e\u043f\u0438\u043e\u043d\u0430\u0442), \u0437\u043e\u043d\u0443\u043b\u0438\u043d, \u043a\u0430\u043b\u044c\u043f\u0440\u043e\u0442\u0435\u043a\u0442\u0438\u043d \u2014 \u0434\u0430\u044e\u0442 \u0431\u043e\u043b\u0435\u0435 \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438 \u0437\u043d\u0430\u0447\u0438\u043c\u0443\u044e \u043a\u0430\u0440\u0442\u0438\u043d\u0443.<\/li><li style=\"font-size:15px;line-height:1.7;color:#1E293B;margin-bottom:7px;\"><b>\u0421\u0435\u0440\u0438\u0439\u043d\u044b\u0435 \u0442\u0435\u0441\u0442\u044b (\u0434\u043e\/\u043f\u043e\u0441\u043b\u0435 \u043f\u0440\u043e\u0442\u043e\u043a\u043e\u043b\u0430)<\/b> \u2014 \u043c\u0430\u043a\u0441\u0438\u043c\u0430\u043b\u044c\u043d\u0430\u044f \u0438\u043d\u0444\u043e\u0440\u043c\u0430\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u044c. \u0420\u0430\u0437\u043e\u0432\u044b\u0439 \u0442\u0435\u0441\u0442 = \u0441\u043d\u0438\u043c\u043e\u043a, \u0441\u0435\u0440\u0438\u044f = \u043a\u0438\u043d\u043e.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-344f5105 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"344f5105\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-4f4e9278\" data-id=\"4f4e9278\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-79ff4bfc elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"79ff4bfc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-20547af4 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"20547af4\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-138003f8\" data-id=\"138003f8\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-65f32ac2 elementor-widget elementor-widget-heading\" data-id=\"65f32ac2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">4. \u041b\u0443\u0447\u0448\u0438\u0435 \u0448\u0442\u0430\u043c\u043c\u044b \u043f\u0440\u043e\u0431\u0438\u043e\u0442\u0438\u043a\u043e\u0432 \u043f\u0440\u0438 \u0434\u044b\u0440\u044f\u0432\u043e\u043c \u043a\u0438\u0448\u0435\u0447\u043d\u0438\u043a\u0435 \u2014 \u0434\u043e\u043a\u0430\u0437\u0430\u0442\u0435\u043b\u044c\u043d\u0430\u044f \u0431\u0430\u0437\u0430<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7dfad55d elementor-widget elementor-widget-text-editor\" data-id=\"7dfad55d\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div style=\"background:#EFF6FF;border-left:4px solid #1E40AF;border-radius:0 8px 8px 0;padding:16px 20px;margin-bottom:16px;\"><b>\u041c\u0435\u0442\u0430-\u0430\u043d\u0430\u043b\u0438\u0437 Ghorbani et al. (Pharmacological Research, 2025):<\/b> 24 RCT, n=1 847. \u041f\u0440\u043e\u0431\u0438\u043e\u0442\u0438\u043a\u0438, \u0441\u0438\u043d\u0431\u0438\u043e\u0442\u0438\u043a\u0438 \u0438 \u043f\u0440\u0435\u0431\u0438\u043e\u0442\u0438\u043a\u0438 \u0434\u043e\u0441\u0442\u043e\u0432\u0435\u0440\u043d\u043e \u0441\u043d\u0438\u0436\u0430\u044e\u0442 \u0437\u043e\u043d\u0443\u043b\u0438\u043d: <b>SMD \u22120.49 (95% CI: 0.32\u20130.66, p<0.001)<\/b> \u0438 \u041b\u041f\u0421: <b>SMD \u22120.61 (95% CI: 0.44\u20130.78)<\/b>. \u042d\u0442\u043e \u043d\u0430\u0438\u0431\u043e\u043b\u0435\u0435 \u0441\u0438\u043b\u044c\u043d\u0430\u044f \u0434\u043e\u043a\u0430\u0437\u0430\u0442\u0435\u043b\u044c\u043d\u0430\u044f \u0431\u0430\u0437\u0430 \u0434\u043b\u044f \u043f\u0440\u043e\u0431\u0438\u043e\u0442\u0438\u043a\u043e\u0432 \u043f\u0440\u0438 leaky gut \u043d\u0430 \u0441\u0435\u0433\u043e\u0434\u043d\u044f\u0448\u043d\u0438\u0439 \u0434\u0435\u043d\u044c.<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-50646772 elementor-widget elementor-widget-heading\" data-id=\"50646772\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">\u0421\u0438\u043d\u0431\u0438\u043e\u0442\u0438\u043a\u0438 vs. \u043f\u0440\u043e\u0431\u0438\u043e\u0442\u0438\u043a\u0438: \u0447\u0442\u043e \u044d\u0444\u0444\u0435\u043a\u0442\u0438\u0432\u043d\u0435\u0435 \u043f\u0440\u0438 leaky gut?<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-7ec28cca elementor-widget elementor-widget-text-editor\" data-id=\"7ec28cca\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p style=\"font-size:16px;line-height:1.75;color:#1E293B;margin:0 0 14px 0;\">\u041f\u043e \u0434\u0430\u043d\u043d\u044b\u043c \u0442\u043e\u0433\u043e \u0436\u0435 \u043c\u0435\u0442\u0430-\u0430\u043d\u0430\u043b\u0438\u0437\u0430 Ghorbani 2025: <b>\u0441\u0438\u043d\u0431\u0438\u043e\u0442\u0438\u043a\u0438<\/b> (\u043f\u0440\u043e\u0431\u0438\u043e\u0442\u0438\u043a + \u043f\u0440\u0435\u0431\u0438\u043e\u0442\u0438\u043a \u0432 \u043e\u0434\u043d\u043e\u043c \u043f\u0440\u0435\u043f\u0430\u0440\u0430\u0442\u0435) \u043f\u043e\u043a\u0430\u0437\u0430\u043b\u0438 <b>\u0431\u043e\u043b\u0435\u0435 \u0432\u044b\u0440\u0430\u0436\u0435\u043d\u043d\u044b\u0439 \u044d\u0444\u0444\u0435\u043a\u0442<\/b> (SMD \u22120.62 vs. \u22120.41 \u0434\u043b\u044f \u0438\u0437\u043e\u043b\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u044b\u0445 \u043f\u0440\u043e\u0431\u0438\u043e\u0442\u0438\u043a\u043e\u0432, p=0.04). \u041c\u0435\u0445\u0430\u043d\u0438\u0437\u043c: \u043f\u0440\u0435\u0431\u0438\u043e\u0442\u0438\u043a \u043e\u0431\u0435\u0441\u043f\u0435\u0447\u0438\u0432\u0430\u0435\u0442 \u0441\u0443\u0431\u0441\u0442\u0440\u0430\u0442 \u0434\u043b\u044f \u0432\u044b\u0436\u0438\u0432\u0430\u043d\u0438\u044f \u0438 \u043a\u043e\u043b\u043e\u043d\u0438\u0437\u0430\u0446\u0438\u0438 \u043f\u0440\u043e\u0431\u0438\u043e\u0442\u0438\u0447\u0435\u0441\u043a\u043e\u0433\u043e \u0448\u0442\u0430\u043c\u043c\u0430, \u0443\u0441\u0438\u043b\u0438\u0432\u0430\u044f \u0438 \u043f\u0440\u043e\u043b\u043e\u043d\u0433\u0438\u0440\u0443\u044f \u0435\u0433\u043e \u044d\u0444\u0444\u0435\u043a\u0442.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-400259c3 elementor-widget elementor-widget-html\" data-id=\"400259c3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<div style=\"overflow-x:auto;margin-bottom:20px;\"><table style=\"width:100%;border-collapse:collapse;font-family:Arial,sans-serif;\"><thead><tr><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u0424\u043e\u0440\u043c\u0430\u0442<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">SMD \u0441\u043d\u0438\u0436\u0435\u043d\u0438\u044f \u0437\u043e\u043d\u0443\u043b\u0438\u043d\u0430 (Ghorbani 2025)<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u041f\u0440\u0435\u0438\u043c\u0443\u0449\u0435\u0441\u0442\u0432\u0430<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u041d\u0435\u0434\u043e\u0441\u0442\u0430\u0442\u043a\u0438<\/th><\/tr><\/thead><tbody><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u041f\u0440\u043e\u0431\u0438\u043e\u0442\u0438\u043a (\u043c\u043e\u043d\u043e\u0448\u0442\u0430\u043c\u043c)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u22120.41 (95% CI: 0.22\u20130.60)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0418\u0437\u0443\u0447\u0435\u043d\u043d\u044b\u0439 \u0448\u0442\u0430\u043c\u043c; \u043f\u0440\u0435\u0434\u0441\u043a\u0430\u0437\u0443\u0435\u043c\u044b\u0439 \u044d\u0444\u0444\u0435\u043a\u0442<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u041c\u0435\u043d\u044c\u0448\u0435 \u0441\u0438\u043d\u0435\u0440\u0433\u0438\u0438; \u043c\u043e\u0436\u0435\u0442 \u043d\u0435 \u043a\u043e\u043b\u043e\u043d\u0438\u0437\u0438\u0440\u043e\u0432\u0430\u0442\u044c \u043f\u0440\u0438 \u0434\u0438\u0441\u0431\u0438\u043e\u0437\u0435<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u041f\u0440\u043e\u0431\u0438\u043e\u0442\u0438\u043a (\u043c\u0443\u043b\u044c\u0442\u0438\u0448\u0442\u0430\u043c\u043c)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u22120.49 (\u043e\u0431\u0449\u0438\u0439)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u041a\u043e\u043c\u043f\u043b\u0435\u043a\u0441\u043d\u043e\u0435 \u0432\u043e\u0437\u0434\u0435\u0439\u0441\u0442\u0432\u0438\u0435; \u043e\u0445\u0432\u0430\u0442\u044b\u0432\u0430\u0435\u0442 \u043d\u0435\u0441\u043a\u043e\u043b\u044c\u043a\u043e \u043c\u0438\u0448\u0435\u043d\u0435\u0439<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0428\u0442\u0430\u043c\u043c\u044b \u043c\u043e\u0433\u0443\u0442 \u043a\u043e\u043d\u043a\u0443\u0440\u0438\u0440\u043e\u0432\u0430\u0442\u044c; \u0441\u043b\u043e\u0436\u043d\u0435\u0435 \u0430\u0442\u0440\u0438\u0431\u0443\u0442\u0438\u0440\u043e\u0432\u0430\u0442\u044c \u044d\u0444\u0444\u0435\u043a\u0442<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0421\u0438\u043d\u0431\u0438\u043e\u0442\u0438\u043a<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u22120.62 (95% CI: 0.39\u20130.85)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u041f\u0440\u0435\u0431\u0438\u043e\u0442\u0438\u043a \u0443\u0441\u0438\u043b\u0438\u0432\u0430\u0435\u0442 \u0432\u044b\u0436\u0438\u0432\u0430\u0435\u043c\u043e\u0441\u0442\u044c; \u043f\u0440\u043e\u043b\u043e\u043d\u0433\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u044b\u0439 \u044d\u0444\u0444\u0435\u043a\u0442<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0411\u043e\u043b\u0435\u0435 \u0441\u043b\u043e\u0436\u043d\u044b\u0439 \u0441\u043e\u0441\u0442\u0430\u0432; \u0432\u044b\u0448\u0435 \u0446\u0435\u043d\u0430<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u041f\u0440\u0435\u0431\u0438\u043e\u0442\u0438\u043a (\u0438\u0437\u043e\u043b\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u044b\u0439)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u22120.38 (95% CI: 0.14\u20130.62)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0421\u0442\u0438\u043c\u0443\u043b\u0438\u0440\u0443\u0435\u0442 \u0441\u043e\u0431\u0441\u0442\u0432\u0435\u043d\u043d\u0443\u044e \u043c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u0442\u0443; \u0431\u0435\u0437 \u043f\u043e\u0431\u043e\u0447\u043d\u044b\u0445 \u0440\u0438\u0441\u043a\u043e\u0432 \u043f\u0440\u043e\u0431\u0438\u043e\u0442\u0438\u043a\u043e\u0432<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u042d\u0444\u0444\u0435\u043a\u0442 \u0437\u0430\u0432\u0438\u0441\u0438\u0442 \u043e\u0442 \u0438\u0441\u0445\u043e\u0434\u043d\u043e\u0433\u043e \u0441\u043e\u0441\u0442\u0430\u0432\u0430 \u043c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u0442\u044b<\/td><\/tr><\/tbody><\/table><p style=\"font-size:12px;color:#64748B;margin-top:6px;\">170,230,250,250<\/p><\/div>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3a27707a elementor-widget elementor-widget-html\" data-id=\"3a27707a\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<div style=\"overflow-x:auto;margin-bottom:20px;\"><table style=\"width:100%;border-collapse:collapse;font-family:Arial,sans-serif;\"><thead><tr><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u0428\u0442\u0430\u043c\u043c<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u041c\u0435\u0445\u0430\u043d\u0438\u0437\u043c \u2191 \u0431\u0430\u0440\u044c\u0435\u0440\u0430<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u0418\u0437\u0443\u0447\u0435\u043d\u043d\u0430\u044f \u0434\u043e\u0437\u0430\/\u0441\u0443\u0442<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u0423\u0440\u043e\u0432\u0435\u043d\u044c \u0434\u043e\u043a\u0430\u0437\u0430\u0442.<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u041f\u0440\u0438\u043c\u0435\u043d\u0435\u043d\u0438\u0435<\/th><\/tr><\/thead><tbody><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">L. rhamnosus GG (LGG)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u2191ZO-1, \u043e\u043a\u043a\u043b\u044e\u0434\u0438\u043d\u0430 \u0447\u0435\u0440\u0435\u0437 PKC\u03b2; \u2191MUC3; \u2193IL-8 \u0438 IL-6; \u2191sIgA<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">1\u201310 \u00d7 10\u2079 \u041a\u041e\u0415<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">High \u2014 >15 RCT, \u043f\u0435\u0434\u0438\u0430\u0442\u0440\u0438\u044f \u0438 \u0432\u0437\u0440\u043e\u0441\u043b\u044b\u0435<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0421\u0420\u041a, \u0434\u0438\u0430\u0440\u0435\u044f, leaky gut, \u0434\u0435\u0442\u0438<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">L. plantarum 299v<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u2193 LPS-\u0442\u0440\u0430\u043d\u0441\u043b\u043e\u043a\u0430\u0446\u0438\u044f; \u2191 TJ-\u0431\u0435\u043b\u043a\u0438 \u043f\u0440\u0438 \u0421\u0420\u041a; \u2193 \u0432\u0438\u0441\u0446\u0435\u0440\u0430\u043b\u044c\u043d\u0430\u044f \u0431\u043e\u043b\u044c<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">10\u00b9\u2070 \u041a\u041e\u0415<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">High \u2014 Nobaek 2000; Haller 2010; RCT \u043f\u0440\u0438 \u041d\u0410\u0416\u0411\u041f<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0421\u0420\u041a, \u041d\u0410\u0416\u0411\u041f, \u0412\u0417\u041a-\u0440\u0435\u043c\u0438\u0441\u0441\u0438\u044f<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">L. reuteri DSM 17938<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0420\u0435\u0443\u0442\u0435\u0440\u0438\u043d \u2192 \u0430\u043d\u0442\u0438\u043c\u0438\u043a\u0440\u043e\u0431\u043d\u044b\u0439; \u2191IL-10; \u2191TJ \u043f\u0440\u0438 \u043a\u043e\u043b\u0438\u0442\u0435 \u0443 \u043c\u044b\u0448\u0435\u0439<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">1 \u00d7 10\u2078 \u041a\u041e\u0415<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">Moderate \u2014 \u043f\u0435\u0434\u0438\u0430\u0442\u0440\u0438\u0447\u0435\u0441\u043a\u0438\u0435 RCT (\u043a\u043e\u043b\u0438\u043a\u0438, \u0434\u0438\u0430\u0440\u0435\u044f)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0414\u0435\u0442\u0438, \u0430\u043d\u0442\u0438\u0431\u0438\u043e\u0442\u0438\u043a-\u0430\u0441\u0441\u043e\u0446. \u0434\u0438\u0430\u0440\u0435\u044f<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">B. longum BB536<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u2191sIgA; \u2193 \u0430\u043b\u043b\u0435\u0440\u0433\u0438\u0447. \u0432\u043e\u0441\u043f\u0430\u043b\u0435\u043d\u0438\u0435; \u2191 \u0431\u0430\u0440\u044c\u0435\u0440 \u0443 \u043f\u043e\u0436\u0438\u043b\u044b\u0445; \u2193IL-6<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">2 \u00d7 10\u2079 \u041a\u041e\u0415<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">Moderate \u2014 RCT 2019 (n=130, \u043f\u043e\u0436\u0438\u043b\u044b\u0435)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u041f\u043e\u0436\u0438\u043b\u044b\u0435, \u0430\u0442\u043e\u043f\u0438\u044f, leaky gut 40+<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">B. infantis 35624<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u2191IL-10\/TGF-\u03b2; \u2193TNF-\u03b1; \u043a\u043e\u0440\u0440\u0435\u043a\u0446\u0438\u044f Th1\/Th2\/Th17 \u0431\u0430\u043b\u0430\u043d\u0441\u0430<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">1 \u00d7 10\u2078 \u041a\u041e\u0415<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">Moderate \u2014 RCT \u043f\u0440\u0438 \u0421\u0420\u041a \u0438 \u0412\u0417\u041a (Whorwell 2006)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0421\u0420\u041a \u0441 \u043f\u0440\u0435\u043e\u0431\u043b\u0430\u0434\u0430\u043d\u0438\u0435\u043c \u0434\u0438\u0430\u0440\u0435\u0438, \u0412\u0417\u041a<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">VSL#3 (8 \u0448\u0442\u0430\u043c\u043c\u043e\u0432)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u2191ZO-1, \u043e\u043a\u043a\u043b\u044e\u0434\u0438\u043d\u0430 \u043f\u0440\u0438 \u041d\u042f\u041a; \u2193\u0437\u043e\u043d\u0443\u043b\u0438\u043d; \u2191\u041a\u0426\u0416\u041a<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">450 \u043c\u043b\u0440\u0434 \u041a\u041e\u0415 (\u041d\u042f\u041a) \/ 112 \u043c\u043b\u0440\u0434 (\u0421\u0420\u041a)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">Moderate-High \u2014 \u041d\u0410\u0416\u0411\u041f, \u041d\u042f\u041a (\u0440\u0435\u043c\u0438\u0441\u0441\u0438\u044f)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0412\u0417\u041a, \u041d\u0410\u0416\u0411\u041f, \u0446\u0438\u0440\u0440\u043e\u0437<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">Saccharomyces boulardii CNCM I-745<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u2193 \u043a\u043b\u0430\u0443\u0434\u0438\u043d-2 (\u043f\u0430\u0442\u043e\u043b. \u043f\u043e\u0440\u044b); \u2191sIgA; \u2193 \u041b\u041f\u0421; \u2191ZO-1<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">250\u2013500 \u043c\u0433<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">Moderate \u2014 C.diff (High), leaky gut (Moderate)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">C.diff, \u0430\u043d\u0442\u0438\u0431\u0438\u043e\u0442\u0438\u043a-\u0434\u0438\u0430\u0440\u0435\u044f, leaky gut<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">Akkermansia muciniphila (\u043f\u0430\u0441\u0442\u0435\u0440.)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u2191MUC2 (\u043c\u0443\u0446\u0438\u043d); \u2191TJ; \u2191GLP-1; \u2193\u044d\u043d\u0434\u043e\u0442\u043e\u043a\u0441\u0435\u043c\u0438\u044f<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">10\u00b9\u2070 \u041a\u041e\u0415 (\u043f\u0430\u0441\u0442\u0435\u0440.)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">Emerging \u2014 RCT Depommier 2021 (n=40, \u043c\u0435\u0442\u0430\u0431.)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u041e\u0436\u0438\u0440\u0435\u043d\u0438\u0435, \u043c\u0435\u0442\u0430\u0431. \u0441\u0438\u043d\u0434\u0440\u043e\u043c, leaky gut<\/td><\/tr><\/tbody><\/table><p style=\"font-size:12px;color:#64748B;margin-top:6px;\">190,250,130,190,160<\/p><\/div>\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-2105c580 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"2105c580\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-6bd4431c\" data-id=\"6bd4431c\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1f15f3b9 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"1f15f3b9\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-275e7c15 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"275e7c15\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-22e83c54\" data-id=\"22e83c54\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-5611abe7 elementor-widget elementor-widget-heading\" data-id=\"5611abe7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">5. \u041f\u043e\u0441\u0442\u0431\u0438\u043e\u0442\u0438\u043a\u0438 \u0438 \u043f\u0440\u0435\u0431\u0438\u043e\u0442\u0438\u043a\u0438: \u0441\u043b\u0435\u0434\u0443\u044e\u0449\u0435\u0435 \u043f\u043e\u043a\u043e\u043b\u0435\u043d\u0438\u0435 \u0442\u0435\u0440\u0430\u043f\u0438\u0438<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-5cb8c6e6 elementor-widget elementor-widget-heading\" data-id=\"5cb8c6e6\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">\u0427\u0442\u043e \u0442\u0430\u043a\u043e\u0435 \u043f\u043e\u0441\u0442\u0431\u0438\u043e\u0442\u0438\u043a\u0438 (ISAPP, 2021)<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4e1e8c24 elementor-widget elementor-widget-text-editor\" data-id=\"4e1e8c24\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p style=\"font-size:16px;line-height:1.75;color:#1E293B;margin:0 0 14px 0;\">\u0421\u043e\u0433\u043b\u0430\u0441\u043d\u043e \u043a\u043e\u043d\u0441\u0435\u043d\u0441\u0443\u0441\u043d\u043e\u043c\u0443 \u043e\u043f\u0440\u0435\u0434\u0435\u043b\u0435\u043d\u0438\u044e ISAPP (International Scientific Association for Probiotics and Prebiotics, 2021): <b>\u00ab\u041f\u043e\u0441\u0442\u0431\u0438\u043e\u0442\u0438\u043a \u2014 \u043f\u0440\u0435\u043f\u0430\u0440\u0430\u0442 \u043d\u0435\u0436\u0438\u0432\u044b\u0445 \u043c\u0438\u043a\u0440\u043e\u043e\u0440\u0433\u0430\u043d\u0438\u0437\u043c\u043e\u0432 \u0438\/\u0438\u043b\u0438 \u0438\u0445 \u043a\u043e\u043c\u043f\u043e\u043d\u0435\u043d\u0442\u043e\u0432, \u043e\u043a\u0430\u0437\u044b\u0432\u0430\u044e\u0449\u0438\u0439 \u043f\u043e\u043b\u044c\u0437\u0443 \u0434\u043b\u044f \u0437\u0434\u043e\u0440\u043e\u0432\u044c\u044f \u0445\u043e\u0437\u044f\u0438\u043d\u0430\u00bb<\/b>. \u042d\u0442\u043e \u041d\u0415 \u043f\u0440\u043e\u0431\u0438\u043e\u0442\u0438\u043a\u0438 (\u0436\u0438\u0432\u044b\u0435) \u0438 \u041d\u0415 \u043f\u0440\u0435\u0431\u0438\u043e\u0442\u0438\u043a\u0438 (\u0441\u0443\u0431\u0441\u0442\u0440\u0430\u0442), \u0430 \u043c\u0435\u0442\u0430\u0431\u043e\u043b\u0438\u0442\u044b \u0438 \u043a\u043e\u043c\u043f\u043e\u043d\u0435\u043d\u0442\u044b \u043c\u0451\u0440\u0442\u0432\u044b\u0445\/\u0438\u043d\u0430\u043a\u0442\u0438\u0432\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u044b\u0445 \u0431\u0430\u043a\u0442\u0435\u0440\u0438\u0439.<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-24280320 elementor-widget elementor-widget-html\" data-id=\"24280320\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<div style=\"overflow-x:auto;margin-bottom:20px;\"><table style=\"width:100%;border-collapse:collapse;font-family:Arial,sans-serif;\"><thead><tr><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u041f\u043e\u0441\u0442\u0431\u0438\u043e\u0442\u0438\u043a<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u0418\u0441\u0442\u043e\u0447\u043d\u0438\u043a<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u041c\u0435\u0445\u0430\u043d\u0438\u0437\u043c \u0432\u043e\u0437\u0434\u0435\u0439\u0441\u0442\u0432\u0438\u044f \u043d\u0430 \u0431\u0430\u0440\u044c\u0435\u0440<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u0414\u043e\u0441\u0442\u0443\u043f\u043d\u043e\u0441\u0442\u044c \u0432 \u0420\u0424<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u0423\u0440\u043e\u0432\u0435\u043d\u044c \u0434\u043e\u043a\u0430\u0437\u0430\u0442.<\/th><\/tr><\/thead><tbody><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0411\u0443\u0442\u0438\u0440\u0430\u0442 (\u043c\u0430\u0441\u043b\u044f\u043d\u0430\u044f \u043a\u0438\u0441\u043b\u043e\u0442\u0430)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0424\u0435\u0440\u043c\u0435\u043d\u0442\u0430\u0446\u0438\u044f F.prausnitzii, Roseburia; \u043c\u0430\u0441\u043b\u043e, \u0441\u044b\u0440<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">HDAC-\u0438\u043d\u0433\u0438\u0431\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u0435 \u2192 \u2191TJ-\u0433\u0435\u043d\u044b; \u043f\u0438\u0442\u0430\u043d\u0438\u0435 \u043a\u043e\u043b\u043e\u043d\u043e\u0446\u0438\u0442\u043e\u0432; \u2191PPAR\u03b3<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0411\u0410\u0414 (\u0431\u0443\u0442\u0438\u0440\u0430\u0442 \u043d\u0430\u0442\u0440\u0438\u044f \u0432 \u043a\u0438\u0448\u0435\u0447\u043d\u043e\u0440\u0430\u0441\u0442\u0432\u043e\u0440\u0438\u043c\u043e\u0439 \u0444\u043e\u0440\u043c\u0435)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">Moderate<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u041f\u0440\u043e\u043f\u0438\u043e\u043d\u0430\u0442<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0424\u0435\u0440\u043c\u0435\u043d\u0442\u0430\u0446\u0438\u044f Bacteroidetes; \u0438\u043d\u0443\u043b\u0438\u043d-\u0424\u041e\u0421<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u2191GPR41\/43 \u2192 \u043f\u0440\u043e\u0442\u0438\u0432\u043e\u0432\u043e\u0441\u043f.; \u2193 \u0433\u043b\u044e\u043a\u043e\u043d\u0435\u043e\u0433\u0435\u043d\u0435\u0437; \u2191\u0446\u0435\u043b\u043e\u0441\u0442\u043d\u043e\u0441\u0442\u044c TJ<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0427\u0435\u0440\u0435\u0437 \u043f\u0438\u0442\u0430\u043d\u0438\u0435 (\u0438\u043d\u0443\u043b\u0438\u043d, \u0424\u041e\u0421)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">Moderate<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0418\u043d\u0434\u043e\u043b\u044b (\u0438\u043d\u0434\u043e\u043b-3-\u043a\u0430\u0440\u0431\u0438\u043d\u043e\u043b)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0424\u0435\u0440\u043c\u0435\u043d\u0442\u0430\u0446\u0438\u044f \u0442\u0440\u0438\u043f\u0442\u043e\u0444\u0430\u043d\u0430 Lactobacillus; \u0431\u0440\u043e\u043a\u043a\u043e\u043b\u0438<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">AhR-\u0430\u0433\u043e\u043d\u0438\u0441\u0442 \u2192 \u2191\u043a\u043b\u0430\u0443\u0434\u0438\u043d-5; \u2191IEL (\u0438\u043d\u0442\u0440\u0430\u044d\u043f\u0438\u0442. \u043b\u0438\u043c\u0444\u043e\u0446\u0438\u0442\u044b)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0411\u0410\u0414 (I3C, DIM)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">Low-Moderate<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u042d\u043a\u0437\u043e\u043f\u043e\u043b\u0438\u0441\u0430\u0445\u0430\u0440\u0438\u0434\u044b (EPS)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u041f\u043e\u0432\u0435\u0440\u0445\u043d\u043e\u0441\u0442\u043d\u044b\u0439 \u0441\u043b\u043e\u0439 Lactobacillus, Bifidobacterium<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u2191MUC2; \u2193\u0430\u0434\u0433\u0435\u0437\u0438\u044f \u043f\u0430\u0442\u043e\u0433\u0435\u043d\u043e\u0432; \u2191sIgA<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0427\u0435\u0440\u0435\u0437 \u043f\u0440\u043e\u0431\u0438\u043e\u0442\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u043f\u0440\u0435\u043f\u0430\u0440\u0430\u0442\u044b<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">Low (in vitro)<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u041f\u0430\u0441\u0442\u0435\u0440\u0438\u0437\u043e\u0432\u0430\u043d\u043d\u0430\u044f Akkermansia<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">Akkermansia muciniphila (\u043d\u0430\u0433\u0440\u0435\u0442\u0430\u044f)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u2191MUC2; \u2191TJ; \u2191GLP-1; \u044d\u0444\u0444\u0435\u043a\u0442 \u0441\u043e\u0445\u0440\u0430\u043d\u044f\u0435\u0442\u0441\u044f \u043f\u043e\u0441\u043b\u0435 \u0438\u043d\u0430\u043a\u0442\u0438\u0432\u0430\u0446\u0438\u0438<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0421\u043f\u0435\u0446\u0438\u0430\u043b\u0438\u0437\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u044b\u0435 \u0411\u0410\u0414 (\u0438\u043c\u043f\u043e\u0440\u0442)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">Emerging \u2014 RCT 2021<\/td><\/tr><\/tbody><\/table><p style=\"font-size:12px;color:#64748B;margin-top:6px;\">180,130,250,170,120<\/p><\/div>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-6b0474ee elementor-widget elementor-widget-heading\" data-id=\"6b0474ee\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">\u041f\u0440\u0435\u0431\u0438\u043e\u0442\u0438\u043a\u0438: \u0441\u0443\u0431\u0441\u0442\u0440\u0430\u0442 \u0434\u043b\u044f \u041a\u0426\u0416\u041a-\u043f\u0440\u043e\u0434\u0443\u0446\u0435\u043d\u0442\u043e\u0432<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-2dafa9ac elementor-widget elementor-widget-html\" data-id=\"2dafa9ac\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<div style=\"overflow-x:auto;margin-bottom:20px;\"><table style=\"width:100%;border-collapse:collapse;font-family:Arial,sans-serif;\"><thead><tr><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u041f\u0440\u0435\u0431\u0438\u043e\u0442\u0438\u043a<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u041e\u0441\u043d\u043e\u0432\u043d\u044b\u0435 \u043f\u0440\u043e\u0434\u0443\u0446\u0438\u0440\u0443\u0435\u043c\u044b\u0435 \u041a\u0426\u0416\u041a<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u0414\u043e\u0437\u0438\u0440\u043e\u0432\u043a\u0430 (RCT)<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u0423\u0440\u043e\u0432\u0435\u043d\u044c \u0434\u043e\u043a\u0430\u0437\u0430\u0442.<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u0418\u0441\u0442\u043e\u0447\u043d\u0438\u043a\u0438 \u0432 \u043f\u0438\u0449\u0435<\/th><\/tr><\/thead><tbody><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0418\u043d\u0443\u043b\u0438\u043d \/ \u0424\u041e\u0421 (\u0444\u0440\u0443\u043a\u0442\u043e\u043e\u043b\u0438\u0433\u043e\u0441\u0430\u0445\u0430\u0440\u0438\u0434\u044b)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0411\u0443\u0442\u0438\u0440\u0430\u0442, \u0430\u0446\u0435\u0442\u0430\u0442<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">5\u201315 \u0433\/\u0441\u0443\u0442<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">Moderate-High<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0426\u0438\u043a\u043e\u0440\u0438\u0439, \u0442\u043e\u043f\u0438\u043d\u0430\u043c\u0431\u0443\u0440, \u0447\u0435\u0441\u043d\u043e\u043a, \u043b\u0443\u043a, \u0430\u0441\u043f\u0430\u0440\u0430\u0433\u0443\u0441<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0413\u041e\u0421 (\u0433\u0430\u043b\u0430\u043a\u0442\u043e\u043e\u043b\u0438\u0433\u043e\u0441\u0430\u0445\u0430\u0440\u0438\u0434\u044b)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0410\u0446\u0435\u0442\u0430\u0442, \u043b\u0430\u043a\u0442\u0430\u0442<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">3\u20135 \u0433\/\u0441\u0443\u0442<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">Moderate \u2014 \u2191Bifidobacterium<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0411\u043e\u0431\u043e\u0432\u044b\u0435, \u0433\u0440\u0443\u0434\u043d\u043e\u0435 \u043c\u043e\u043b\u043e\u043a\u043e<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u041f\u0435\u043a\u0442\u0438\u043d (\u0446\u0438\u0442\u0440\u0443\u0441\u043e\u0432\u044b\u0439, \u044f\u0431\u043b\u043e\u0447\u043d\u044b\u0439)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0411\u0443\u0442\u0438\u0440\u0430\u0442, \u043f\u0440\u043e\u043f\u0438\u043e\u043d\u0430\u0442<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">6\u201324 \u0433\/\u0441\u0443\u0442<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">Moderate<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u042f\u0431\u043b\u043e\u043a\u0438 (\u0441 \u043a\u043e\u0436\u0443\u0440\u043e\u0439), \u0446\u0438\u0442\u0440\u0443\u0441\u044b, \u0441\u0432\u0451\u043a\u043b\u0430, \u043c\u043e\u0440\u043a\u043e\u0432\u044c<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0420\u0435\u0437\u0438\u0441\u0442\u0435\u043d\u0442\u043d\u044b\u0439 \u043a\u0440\u0430\u0445\u043c\u0430\u043b (RS2, RS3)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0411\u0443\u0442\u0438\u0440\u0430\u0442 (\u0433\u043b\u0430\u0432\u043d\u044b\u0439)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">10\u201320 \u0433\/\u0441\u0443\u0442<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">High \u2014 \u2191F.prausnitzii<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u041e\u0445\u043b. \u043a\u0430\u0440\u0442\u043e\u0444\u0435\u043b\u044c, \u043e\u0445\u043b. \u0440\u0438\u0441, \u0437\u0435\u043b\u0451\u043d\u044b\u0435 \u0431\u0430\u043d\u0430\u043d\u044b, \u0431\u043e\u0431\u043e\u0432\u044b\u0435<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0411\u0435\u0442\u0430-\u0433\u043b\u044e\u043a\u0430\u043d\u044b (\u043e\u0432\u0441\u044f\u043d\u044b\u0435)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u041f\u0440\u043e\u043f\u0438\u043e\u043d\u0430\u0442, \u0430\u0446\u0435\u0442\u0430\u0442<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">3\u20136 \u0433\/\u0441\u0443\u0442<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">Moderate<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u041e\u0432\u0451\u0441, \u044f\u0447\u043c\u0435\u043d\u044c, \u0433\u0440\u0438\u0431\u044b<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0410\u0440\u0430\u0431\u0438\u043d\u043e\u043a\u0441\u0438\u043b\u0430\u043d (AXOS)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0411\u0443\u0442\u0438\u0440\u0430\u0442, \u0430\u0446\u0435\u0442\u0430\u0442<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">3\u201310 \u0433\/\u0441\u0443\u0442<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">Moderate \u2014 \u2191Bifidobacterium<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u041f\u0448\u0435\u043d\u0438\u0447\u043d\u044b\u0435 \u043e\u0442\u0440\u0443\u0431\u0438, \u0437\u043b\u0430\u043a\u0438<\/td><\/tr><\/tbody><\/table><p style=\"font-size:12px;color:#64748B;margin-top:6px;\">200,160,130,140,210<\/p><\/div>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1839fe1e elementor-widget elementor-widget-text-editor\" data-id=\"1839fe1e\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div style=\"background:#FFFBEB;border-left:4px solid #D97706;border-radius:0 8px 8px 0;padding:16px 20px;margin-bottom:16px;\"><b>\u041f\u0440\u0430\u043a\u0442\u0438\u0447\u0435\u0441\u043a\u0430\u044f \u0440\u0435\u043a\u043e\u043c\u0435\u043d\u0434\u0430\u0446\u0438\u044f:<\/b> \u041d\u0430\u0447\u0438\u043d\u0430\u0442\u044c \u043f\u0440\u0435\u0431\u0438\u043e\u0442\u0438\u043a\u0438 \u0441 \u043c\u0438\u043d\u0438\u043c\u0430\u043b\u044c\u043d\u044b\u0445 \u0434\u043e\u0437 (1\u20132 \u0433\/\u0441\u0443\u0442) \u0441 \u043f\u043e\u0441\u0442\u0435\u043f\u0435\u043d\u043d\u044b\u043c \u0443\u0432\u0435\u043b\u0438\u0447\u0435\u043d\u0438\u0435\u043c \u0440\u0430\u0437 \u0432 \u043d\u0435\u0434\u0435\u043b\u044e. \u0420\u0435\u0437\u043a\u043e\u0435 \u0432\u0432\u0435\u0434\u0435\u043d\u0438\u0435 \u0432\u044b\u0441\u043e\u043a\u0438\u0445 \u0434\u043e\u0437 \u0443 \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432 \u0441 \u0421\u0418\u0411\u041e \u043c\u043e\u0436\u0435\u0442 \u0432\u044b\u0437\u0432\u0430\u0442\u044c \u0432\u044b\u0440\u0430\u0436\u0435\u043d\u043d\u044b\u0439 \u0434\u0438\u0441\u043a\u043e\u043c\u0444\u043e\u0440\u0442 (\u0433\u0430\u0437\u043e\u043e\u0431\u0440\u0430\u0437\u043e\u0432\u0430\u043d\u0438\u0435, \u0432\u0437\u0434\u0443\u0442\u0438\u0435). \u041f\u0440\u0438 \u043f\u043e\u0434\u043e\u0437\u0440\u0435\u043d\u0438\u0438 \u043d\u0430 \u0421\u0418\u0411\u041e \u2014 \u0441\u043d\u0430\u0447\u0430\u043b\u0430 \u0435\u0433\u043e \u043b\u0435\u0447\u0435\u043d\u0438\u0435, \u0437\u0430\u0442\u0435\u043c \u043f\u0440\u0435\u0431\u0438\u043e\u0442\u0438\u043a\u0438.<\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-66246cec elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"66246cec\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-e626c63\" data-id=\"e626c63\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4c97a1c5 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"4c97a1c5\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-791c67c9 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"791c67c9\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-4340a261\" data-id=\"4340a261\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-7151d5a8 elementor-widget elementor-widget-heading\" data-id=\"7151d5a8\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">6. Gut-brain \u0438 gut-skin axis: \u043a\u0430\u043a \u043c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u043c \u0432\u043b\u0438\u044f\u0435\u0442 \u043d\u0430 \u043c\u043e\u0437\u0433 \u0438 \u043a\u043e\u0436\u0443<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-1dd71913 elementor-widget elementor-widget-heading\" data-id=\"1dd71913\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Gut-brain axis: \u043a\u0438\u0448\u0435\u0447\u043d\u0438\u043a \u043a\u0430\u043a \u00ab\u0432\u0442\u043e\u0440\u043e\u0439 \u043c\u043e\u0437\u0433\u00bb<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-25b2dba0 elementor-widget elementor-widget-text-editor\" data-id=\"25b2dba0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p style=\"font-size:16px;line-height:1.75;color:#1E293B;margin:0 0 14px 0;\">\u041e\u0441\u044c \u043a\u0438\u0448\u0435\u0447\u043d\u0438\u043a\u2013\u043c\u043e\u0437\u0433 (gut-brain axis) \u2014 \u0434\u0432\u0443\u043d\u0430\u043f\u0440\u0430\u0432\u043b\u0435\u043d\u043d\u0430\u044f \u043a\u043e\u043c\u043c\u0443\u043d\u0438\u043a\u0430\u0446\u0438\u043e\u043d\u043d\u0430\u044f \u0441\u0435\u0442\u044c, \u0432\u043a\u043b\u044e\u0447\u0430\u044e\u0449\u0430\u044f:<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-13e4deca elementor-widget elementor-widget-text-editor\" data-id=\"13e4deca\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<ul style=\"padding-left:22px;margin:0 0 16px 0;\"><li style=\"font-size:15px;line-height:1.7;color:#1E293B;margin-bottom:7px;\"><b>\u0411\u043b\u0443\u0436\u0434\u0430\u044e\u0449\u0438\u0439 \u043d\u0435\u0440\u0432<\/b> (n. vagus) \u2014 \u043f\u0440\u044f\u043c\u043e\u0439 \u00ab\u043f\u0440\u043e\u0432\u043e\u0434\u00bb \u043e\u0442 \u043a\u0438\u0448\u0435\u0447\u043d\u0438\u043a\u0430 \u043a \u043c\u043e\u0437\u0433\u0443; \u043f\u0435\u0440\u0435\u0434\u0430\u0451\u0442 \u0441\u0438\u0433\u043d\u0430\u043b\u044b \u043e \u0441\u043e\u0441\u0442\u043e\u044f\u043d\u0438\u0438 \u043c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u0442\u044b (80% \u0441\u0438\u0433\u043d\u0430\u043b\u043e\u0432 \u2014 \u0441\u043d\u0438\u0437\u0443 \u0432\u0432\u0435\u0440\u0445).<\/li><li style=\"font-size:15px;line-height:1.7;color:#1E293B;margin-bottom:7px;\"><b>\u041d\u0435\u0439\u0440\u043e\u0442\u0440\u0430\u043d\u0441\u043c\u0438\u0442\u0442\u0435\u0440\u044b<\/b>: \u043a\u0438\u0448\u0435\u0447\u043d\u0438\u043a \u043f\u0440\u043e\u0438\u0437\u0432\u043e\u0434\u0438\u0442 <b>90% \u0441\u0435\u0440\u043e\u0442\u043e\u043d\u0438\u043d\u0430<\/b> \u043e\u0440\u0433\u0430\u043d\u0438\u0437\u043c\u0430 (\u0447\u0435\u0440\u0435\u0437 \u044d\u043d\u0442\u0435\u0440\u043e\u0445\u0440\u043e\u043c\u0430\u0444\u0444\u0438\u043d\u043d\u044b\u0435 \u043a\u043b\u0435\u0442\u043a\u0438). \u0414\u0438\u0441\u0431\u0438\u043e\u0437 \u2192 \u043d\u0430\u0440\u0443\u0448\u0435\u043d\u0438\u0435 \u0441\u0438\u043d\u0442\u0435\u0437\u0430 \u0441\u0435\u0440\u043e\u0442\u043e\u043d\u0438\u043d\u0430 \u2192 \u0434\u0435\u043f\u0440\u0435\u0441\u0441\u0438\u044f, \u0442\u0440\u0435\u0432\u043e\u0436\u043d\u043e\u0441\u0442\u044c.<\/li><li style=\"font-size:15px;line-height:1.7;color:#1E293B;margin-bottom:7px;\"><b>\u0418\u043c\u043c\u0443\u043d\u043d\u044b\u0435 \u043c\u0435\u0434\u0438\u0430\u0442\u043e\u0440\u044b<\/b>: \u041b\u041f\u0421 \u0438 \u043f\u0440\u043e\u0432\u043e\u0441\u043f\u0430\u043b\u0438\u0442. \u0446\u0438\u0442\u043e\u043a\u0438\u043d\u044b (TNF-\u03b1, IL-6) \u043f\u0440\u043e\u043d\u0438\u043a\u0430\u044e\u0442 \u0447\u0435\u0440\u0435\u0437 \u0413\u042d\u0411 \u2192 \u043d\u0435\u0439\u0440\u043e\u0432\u043e\u0441\u043f\u0430\u043b\u0435\u043d\u0438\u0435 \u2192 \u0441\u043d\u0438\u0436\u0435\u043d\u0438\u0435 BDNF (\u043d\u0435\u0439\u0440\u043e\u0442\u0440\u043e\u0444\u0438\u0447\u0435\u0441\u043a\u0438\u0439 \u0444\u0430\u043a\u0442\u043e\u0440) \u2192 \u0434\u0435\u043f\u0440\u0435\u0441\u0441\u0438\u044f.<\/li><li style=\"font-size:15px;line-height:1.7;color:#1E293B;margin-bottom:7px;\"><b>\u041a\u0426\u0416\u041a<\/b>: \u0431\u0443\u0442\u0438\u0440\u0430\u0442 \u0438 \u043f\u0440\u043e\u043f\u0438\u043e\u043d\u0430\u0442 \u043f\u0435\u0440\u0435\u0441\u0435\u043a\u0430\u044e\u0442 \u0413\u042d\u0411, \u0432\u043b\u0438\u044f\u044f \u043d\u0430 \u043d\u0435\u0439\u0440\u043e\u0432\u043e\u0441\u043f\u0430\u043b\u0435\u043d\u0438\u0435, \u0444\u0443\u043d\u043a\u0446\u0438\u044e \u043c\u0438\u0442\u043e\u0445\u043e\u043d\u0434\u0440\u0438\u0439 \u043d\u0435\u0439\u0440\u043e\u043d\u043e\u0432 \u0438 \u044d\u043a\u0441\u043f\u0440\u0435\u0441\u0441\u0438\u044e BDNF.<\/li><\/ul>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-729dc0a2 elementor-widget elementor-widget-html\" data-id=\"729dc0a2\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<div style=\"overflow-x:auto;margin-bottom:20px;\"><table style=\"width:100%;border-collapse:collapse;font-family:Arial,sans-serif;\"><thead><tr><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u0421\u043e\u0441\u0442\u043e\u044f\u043d\u0438\u0435<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u041c\u0435\u0445\u0430\u043d\u0438\u0437\u043c gut-brain<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u0414\u0430\u043d\u043d\u044b\u0435<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u0423\u0440\u043e\u0432\u0435\u043d\u044c \u0434\u043e\u043a\u0430\u0437\u0430\u0442\u0435\u043b\u044c\u043d\u043e\u0441\u0442\u0438<\/th><\/tr><\/thead><tbody><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0411\u043e\u043b\u044c\u0448\u043e\u0435 \u0434\u0435\u043f\u0440\u0435\u0441\u0441\u0438\u0432\u043d\u043e\u0435 \u0440\u0430\u0441\u0441\u0442\u0440\u043e\u0439\u0441\u0442\u0432\u043e<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">LPS\u2192\u043d\u0435\u0439\u0440\u043e\u0432\u043e\u0441\u043f\u0430\u043b\u0435\u043d\u0438\u0435\u2192\u2193BDNF; \u2193\u0441\u0435\u0440\u043e\u0442\u043e\u043d\u0438\u043d\u043e\u0432\u044b\u0435 \u043c\u0435\u0442\u0430\u0431\u043e\u043b\u0438\u0442\u044b \u043f\u0440\u0438 \u0434\u0438\u0441\u0431\u0438\u043e\u0437\u0435<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u041c\u0435\u0442\u0430-\u0430\u043d\u0430\u043b\u0438\u0437 2021: LBP\u2191 \u043f\u0440\u0438 \u0411\u0414\u0420 (OR 1.8, p<0.01)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">Moderate<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0422\u0440\u0435\u0432\u043e\u0436\u043d\u044b\u0435 \u0440\u0430\u0441\u0441\u0442\u0440\u043e\u0439\u0441\u0442\u0432\u0430<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u2191\u043f\u0440\u043e\u0432\u043e\u0441\u043f\u0430\u043b\u0438\u0442. \u0446\u0438\u0442\u043e\u043a\u0438\u043d\u044b \u2192 \u0430\u043a\u0442\u0438\u0432\u0430\u0446\u0438\u044f \u043c\u0438\u043d\u0434\u0430\u043b\u0438\u043d\u044b; \u2193GABA \u043f\u0440\u0438 \u0434\u0438\u0441\u0431\u0438\u043e\u0437\u0435<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">RCT: L.rhamnosus \u0441\u043d\u0438\u0436\u0430\u0435\u0442 \u0442\u0440\u0435\u0432\u043e\u0436\u043d\u043e\u0441\u0442\u044c \u0443 \u043c\u044b\u0448\u0435\u0439 (Bravo, PNAS, 2011)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">Low-Moderate (\u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u0434\u0430\u043d\u043d\u044b\u0435 \u043e\u0433\u0440\u0430\u043d\u0438\u0447\u0435\u043d\u044b)<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">ME\/CFS (\u0445\u0440. \u0443\u0441\u0442\u0430\u043b\u043e\u0441\u0442\u044c)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0411\u0430\u043a\u0442\u0435\u0440\u0438\u0430\u043b\u044c\u043d\u0430\u044f \u0442\u0440\u0430\u043d\u0441\u043b\u043e\u043a\u0430\u0446\u0438\u044f \u2192 \u0445\u0440. \u043d\u0435\u0439\u0440\u043e\u0432\u043e\u0441\u043f\u0430\u043b\u0435\u043d\u0438\u0435 \u2192 \u043c\u0438\u0442\u043e\u0445\u043e\u043d\u0434\u0440. \u0434\u0438\u0441\u0444\u0443\u043d\u043a\u0446\u0438\u044f<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0421\u043f\u0435\u0446\u0438\u0444\u0438\u0447\u0435\u0441\u043a\u0438\u0439 \u0434\u0438\u0441\u0431\u0438\u043e\u0437 \u043f\u0440\u0438 ME\/CFS (Giloteaux, Microbiome, 2016)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">Moderate \u2014 \u0430\u0441\u0441\u043e\u0446\u0438\u0430\u0446\u0438\u044f, \u043d\u0435 \u043f\u0440\u0438\u0447\u0438\u043d\u043d\u043e\u0441\u0442\u044c<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0411\u043e\u043b\u0435\u0437\u043d\u044c \u0410\u043b\u044c\u0446\u0433\u0435\u0439\u043c\u0435\u0440\u0430<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0414\u0438\u0441\u0431\u0438\u043e\u0437 \u2192 \u2191\u03b2-\u0430\u043c\u0438\u043b\u043e\u0438\u0434; LPS \u2192 \u043d\u0435\u0439\u0440\u043e\u0432\u043e\u0441\u043f\u0430\u043b\u0435\u043d\u0438\u0435 (\u0430\u0441\u0442\u0440\u043e\u0446\u0438\u0442\u044b)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0421\u043f\u0435\u0446\u0438\u0444\u0438\u0447\u0435\u0441\u043a\u0438\u0435 \u043f\u0430\u0442\u0442\u0435\u0440\u043d\u044b \u043c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u043c\u0430 \u043f\u0440\u0438 \u0411\u0410 (Vogt, Sci Rep, 2017)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">Low \u2014 \u043f\u0440\u0435\u043a\u043b\u0438\u043d\u0438\u043a\u0430 \u0438 \u0430\u0441\u0441\u043e\u0446\u0438\u0430\u0442\u0438\u0432\u043d\u044b\u0435<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0411\u043e\u043b\u0435\u0437\u043d\u044c \u041f\u0430\u0440\u043a\u0438\u043d\u0441\u043e\u043d\u0430<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0421\u0438\u043d\u0443\u043a\u043b\u0435\u0438\u043d\u043e\u043f\u0430\u0442\u0438\u044f \u043d\u0430\u0447\u0438\u043d\u0430\u0435\u0442\u0441\u044f \u0432 \u043a\u0438\u0448\u0435\u0447\u043d\u0438\u043a\u0435 (Braak hypothesis), \u0434\u0438\u0441\u0431\u0438\u043e\u0437 \u043f\u0440\u0435\u0434\u0448\u0435\u0441\u0442\u0432\u0443\u0435\u0442<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u041a\u043e\u043d\u0441\u0442\u0438\u043f\u0430\u0446\u0438\u044f \u0437\u0430 10\u201320 \u043b\u0435\u0442 \u0434\u043e \u043c\u043e\u0442\u043e\u0440\u043d\u044b\u0445 \u0441\u0438\u043c\u043f\u0442\u043e\u043c\u043e\u0432; \u0441\u043f\u0435\u0446\u0438\u0444. \u0434\u0438\u0441\u0431\u0438\u043e\u0437<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">Moderate \u2014 \u0431\u043e\u043b\u044c\u0448\u0438\u0435 \u043a\u043e\u0433\u043e\u0440\u0442\u043d\u044b\u0435<\/td><\/tr><\/tbody><\/table><p style=\"font-size:12px;color:#64748B;margin-top:6px;\">180,240,240,160<\/p><\/div>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-122852e3 elementor-widget elementor-widget-heading\" data-id=\"122852e3\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h3 class=\"elementor-heading-title elementor-size-default\">Gut-skin axis: \u043a\u0438\u0448\u0435\u0447\u043d\u0438\u043a \u043a\u0430\u043a \u0437\u0435\u0440\u043a\u0430\u043b\u043e \u043a\u043e\u0436\u0438<\/h3>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3333d9b7 elementor-widget elementor-widget-text-editor\" data-id=\"3333d9b7\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p style=\"font-size:16px;line-height:1.75;color:#1E293B;margin:0 0 14px 0;\">\u0421\u0432\u044f\u0437\u044c \u043a\u0438\u0448\u0435\u0447\u043d\u0438\u043a\u2013\u043a\u043e\u0436\u0430 \u0440\u0435\u0430\u043b\u0438\u0437\u0443\u0435\u0442\u0441\u044f \u0447\u0435\u0440\u0435\u0437 \u0442\u0440\u0438 \u043e\u0441\u043d\u043e\u0432\u043d\u044b\u0445 \u043f\u0443\u0442\u0438: <b>\u0438\u043c\u043c\u0443\u043d\u043d\u044b\u0439<\/b> (\u0441\u0438\u0441\u0442\u0435\u043c\u043d\u043e\u0435 \u0432\u043e\u0441\u043f\u0430\u043b\u0435\u043d\u0438\u0435 \u2192 \u043d\u0435\u0439\u0440\u043e\u0433\u0435\u043d\u043d\u043e\u0435 \u0432\u043e\u0441\u043f\u0430\u043b\u0435\u043d\u0438\u0435 \u043a\u043e\u0436\u0438), <b>\u043d\u0435\u0439\u0440\u043e\u044d\u043d\u0434\u043e\u043a\u0440\u0438\u043d\u043d\u044b\u0439<\/b> (\u0433\u043e\u0440\u043c\u043e\u043d\u044b \u0441\u0442\u0440\u0435\u0441\u0441\u0430, \u043a\u043e\u0440\u0442\u0438\u0437\u043e\u043b \u2192 \u043a\u043e\u0436\u0430 \u0447\u0435\u0440\u0435\u0437 \u0433\u0438\u043f\u043e\u0442\u0430\u043b\u0430\u043c\u043e-\u0433\u0438\u043f\u043e\u0444\u0438\u0437\u0430\u0440\u043d\u043e-\u043d\u0430\u0434\u043f\u043e\u0447\u0435\u0447\u043d\u0438\u043a\u043e\u0432\u0443\u044e \u043e\u0441\u044c) \u0438 <b>\u043c\u0435\u0442\u0430\u0431\u043e\u043b\u0438\u0447\u0435\u0441\u043a\u0438\u0439<\/b> (\u043a\u0438\u0448\u0435\u0447\u043d\u044b\u0435 \u043c\u0435\u0442\u0430\u0431\u043e\u043b\u0438\u0442\u044b \u2192 \u0441\u0438\u0441\u0442\u0435\u043c\u043d\u0430\u044f \u0446\u0438\u0440\u043a\u0443\u043b\u044f\u0446\u0438\u044f \u2192 \u043a\u043e\u0436\u0430).<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4c8eb9ac elementor-widget elementor-widget-html\" data-id=\"4c8eb9ac\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<div style=\"overflow-x:auto;margin-bottom:20px;\"><table style=\"width:100%;border-collapse:collapse;font-family:Arial,sans-serif;\"><thead><tr><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u041a\u043e\u0436\u043d\u043e\u0435 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0435<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u0421\u0432\u044f\u0437\u044c \u0441 \u0434\u0438\u0441\u0431\u0438\u043e\u0437\u043e\u043c\/leaky gut<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u0414\u0430\u043d\u043d\u044b\u0435<\/th><th style=\"background:#DBEAFE;color:#1E3A8A;font-weight:700;font-size:13px;padding:10px 12px;text-align:left;border:1px solid #93C5FD;white-space:nowrap;\">\u0422\u0435\u0440\u0430\u043f\u0435\u0432\u0442\u0438\u0447\u0435\u0441\u043a\u0438\u0439 \u043f\u043e\u0442\u0435\u043d\u0446\u0438\u0430\u043b<\/th><\/tr><\/thead><tbody><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0410\u043a\u043d\u0435 \u0432\u0443\u043b\u044c\u0433\u0430\u0440\u0438\u0441<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0414\u0438\u0441\u0431\u0438\u043e\u0437 \u2192 \u0441\u0438\u0441\u0442\u0435\u043c\u043d\u043e\u0435 \u0432\u043e\u0441\u043f\u0430\u043b\u0435\u043d\u0438\u0435 \u2192 \u2191IGF-1 \u0438 mTOR \u0432 \u043a\u043e\u0436\u0435 \u2192 \u0433\u0438\u043f\u0435\u0440\u0441\u0435\u0431\u0443\u043c + P.acnes \u0440\u043e\u0441\u0442<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0421\u043f\u0435\u0446\u0438\u0444. \u0434\u0438\u0441\u0431\u0438\u043e\u0437 \u043f\u0440\u0438 \u0430\u043a\u043d\u0435 (Fabbrocini, 2018); \u043f\u0440\u043e\u0431\u0438\u043e\u0442\u0438\u043a\u0438 \u2192 \u2193 \u0432\u043e\u0441\u043f\u0430\u043b\u0435\u043d\u0438\u0435 \u043a\u043e\u0436\u0438 (RCT)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">L.rhamnosus GG; \u0446\u0438\u043d\u043a \u043f\u0435\u0440\u043e\u0440\u0430\u043b\u044c\u043d\u043e<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0410\u0442\u043e\u043f\u0438\u0447\u0435\u0441\u043a\u0438\u0439 \u0434\u0435\u0440\u043c\u0430\u0442\u0438\u0442 (\u0410\u0414)<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">Gut dysbiosis \u043f\u0440\u0435\u0434\u0448\u0435\u0441\u0442\u0432\u0443\u0435\u0442 \u0410\u0414 \u0443 \u043c\u043b\u0430\u0434\u0435\u043d\u0446\u0435\u0432; \u2193Bifidobacterium \u2192 \u2191Th2 \u2192 \u0430\u0442\u043e\u043f\u0438\u044f<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u041c\u0435\u0442\u0430-\u0430\u043d\u0430\u043b\u0438\u0437: \u043f\u0440\u043e\u0431\u0438\u043e\u0442\u0438\u043a\u0438 \u043f\u0440\u0438 \u0410\u0414 (Cochrane 2018); L.rhamnosus GG \u0441\u043d\u0438\u0436\u0430\u0435\u0442 SCORAD<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u041f\u0440\u043e\u0431\u0438\u043e\u0442\u0438\u043a\u0438 \u0432 \u043f\u0440\u0435\u043d\u0430\u0442\u0430\u043b\u044c\u043d\u043e\u043c + \u043f\u043e\u0441\u0442\u043d\u0430\u0442\u0430\u043b\u044c\u043d\u043e\u043c \u043f\u0435\u0440\u0438\u043e\u0434\u0435<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u041f\u0441\u043e\u0440\u0438\u0430\u0437<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">Leaky gut \u2192 \u0430\u0443\u0442\u043e\u0430\u043d\u0442\u0438\u0433\u0435\u043d\u044b \u2192 Th17\/IL-17 \u0430\u043a\u0442\u0438\u0432\u0430\u0446\u0438\u044f; \u2191\u0437\u043e\u043d\u0443\u043b\u0438\u043d \u0443 30\u201340% \u043f\u0430\u0446\u0438\u0435\u043d\u0442\u043e\u0432<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0421\u043f\u0435\u0446\u0438\u0444. \u0434\u0438\u0441\u0431\u0438\u043e\u0437 \u043f\u0440\u0438 \u043f\u0441\u043e\u0440\u0438\u0430\u0437\u0435 (Scher, 2015); FMT-\u0441\u043b\u0443\u0447\u0430\u0438 \u0440\u0435\u043c\u0438\u0441\u0441\u0438\u0438<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">Emerging \u2014 \u043f\u0440\u043e\u0431\u0438\u043e\u0442\u0438\u043a\u0438 + FMT (\u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f \u0438\u0434\u0443\u0442)<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0420\u043e\u0437\u0430\u0446\u0435\u0430<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0421\u0418\u0411\u041e \u2192 \u0445\u0440. \u0441\u0438\u0441\u0442\u0435\u043c\u043d\u043e\u0435 \u0432\u043e\u0441\u043f\u0430\u043b\u0435\u043d\u0438\u0435 \u2192 \u043d\u0435\u0439\u0440\u043e\u0433\u0435\u043d\u043d\u0430\u044f \u0432\u0430\u0437\u043e\u0434\u0438\u043b\u0430\u0442\u0430\u0446\u0438\u044f \u043b\u0438\u0446\u0430<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0421\u0418\u0411\u041e \u0443 70% \u043f\u0440\u0438 \u0440\u043e\u0437\u0430\u0446\u0435\u0430 (Parodi, 2008); \u044d\u0440\u0430\u0434\u0438\u043a\u0430\u0446\u0438\u044f \u0421\u0418\u0411\u041e \u2192 \u0440\u0435\u043c\u0438\u0441\u0441\u0438\u044f \u0443 \u0447\u0430\u0441\u0442\u0438<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#FFFFFF;vertical-align:top;line-height:1.5;\">\u0420\u0438\u0444\u0430\u043a\u0441\u0438\u043c\u0438\u043d \u043f\u0440\u0438 \u0421\u0418\u0411\u041e + \u043f\u0440\u043e\u0431\u0438\u043e\u0442\u0438\u043a\u0438<\/td><\/tr><tr><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0421\u0435\u0431\u043e\u0440\u0435\u0439\u043d\u044b\u0439 \u0434\u0435\u0440\u043c\u0430\u0442\u0438\u0442<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0414\u0438\u0441\u0431\u0438\u043e\u0437 + \u0433\u0440\u0438\u0431\u043a\u043e\u0432\u044b\u0439 \u0434\u0438\u0441\u0431\u0430\u043b\u0430\u043d\u0441 (Malassezia) + \u2191LPS \u2192 \u0432\u043e\u0441\u043f\u0430\u043b\u0435\u043d\u0438\u0435 \u043a\u043e\u0436\u0438 \u0433\u043e\u043b\u043e\u0432\u044b<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u0410\u0441\u0441\u043e\u0446\u0438\u0430\u0446\u0438\u044f \u0434\u0438\u0441\u0431\u0438\u043e\u0437\u0430 \u0441 Malassezia-\u0430\u043a\u0442\u0438\u0432\u043d\u043e\u0441\u0442\u044c\u044e<\/td><td style=\"padding:9px 12px;border:1px solid #CBD5E1;font-size:13px;color:#1E293B;background:#F8FAFC;vertical-align:top;line-height:1.5;\">\u041f\u0440\u043e\u0431\u0438\u043e\u0442\u0438\u043a\u0438 (Lactobacillus paracasei); \u043e\u0433\u0440\u0430\u043d\u0438\u0447\u0435\u043d\u043d\u044b\u0435 RCT<\/td><\/tr><\/tbody><\/table><p style=\"font-size:12px;color:#64748B;margin-top:6px;\">170,240,240,180<\/p><\/div>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-3b6a19cc elementor-widget elementor-widget-text-editor\" data-id=\"3b6a19cc\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div style=\"background: #F0F9FF; border: 1px solid #BAE6FD; border-radius: 8px; padding: 12px 18px; margin-bottom: 10px;\"><p><span style=\"color: #0284c7; font-size: 15px; font-weight: 600;\">\u2192 <\/span><a style=\"color: #0284c7; font-size: 15px; font-weight: 600; text-decoration: none;\" href=\"https:\/\/novolakrb1.ru\/statii\/povyshennaya-pronicaemost-kishechnika\/\">\u041f\u043e\u0432\u044b\u0448\u0435\u043d\u043d\u0430\u044f \u043f\u0440\u043e\u043d\u0438\u0446\u0430\u0435\u043c\u043e\u0441\u0442\u044c \u043a\u0438\u0448\u0435\u0447\u043d\u0438\u043a\u0430 \u043a\u0430\u043a \u043c\u0435\u0445\u0430\u043d\u0438\u0437\u043c \u0430\u0443\u0442\u043e\u0438\u043c\u043c\u0443\u043d\u043d\u044b\u0445 \u0438 \u0441\u0438\u0441\u0442\u0435\u043c\u043d\u044b\u0445 \u0437\u0430\u0431\u043e\u043b\u0435\u0432\u0430\u043d\u0438\u0439<\/a><\/p><\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-78d97292 elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"78d97292\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-313dccd0\" data-id=\"313dccd0\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-395745f0 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"395745f0\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-62b612f elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"62b612f\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-7fe243b3\" data-id=\"7fe243b3\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-4ba0f087 elementor-widget elementor-widget-heading\" data-id=\"4ba0f087\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"heading.default\">\n\t\t\t\t\t<h2 class=\"elementor-heading-title elementor-size-default\">FAQ \u2014 \u0427\u0430\u0441\u0442\u043e \u0437\u0430\u0434\u0430\u0432\u0430\u0435\u043c\u044b\u0435 \u0432\u043e\u043f\u0440\u043e\u0441\u044b<\/h2>\t\t\t\t<\/div>\n\t\t\t\t<div class=\"elementor-element elementor-element-4a2abb77 elementor-widget elementor-widget-text-editor\" data-id=\"4a2abb77\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<div style=\"margin-bottom:8px;\">\n    <details style=\"border:1px solid #CBD5E1;border-radius:8px;margin-bottom:8px;overflow:hidden;\">\n      <summary style=\"font-size:15px;font-weight:700;color:#1E293B;padding:14px 18px;cursor:pointer;background:#F8FAFC;list-style:none;display:flex;align-items:center;justify-content:space-between;\">\n        \u041a\u0430\u043a \u0434\u0438\u0441\u0431\u0438\u043e\u0437 \u0432\u044b\u0437\u044b\u0432\u0430\u0435\u0442 \u0434\u044b\u0440\u044f\u0432\u044b\u0439 \u043a\u0438\u0448\u0435\u0447\u043d\u0438\u043a?\n        <span style=\"font-size:20px;color:#1E40AF;font-weight:300;\">+<\/span>\n      <\/summary>\n      <div style=\"padding:14px 18px 16px 18px;background:#FFFFFF;font-size:15px;line-height:1.7;color:#1E293B;\">\n        \u041f\u0440\u0438 \u0434\u0438\u0441\u0431\u0438\u043e\u0437\u0435 \u0441\u043d\u0438\u0436\u0430\u044e\u0442\u0441\u044f \u041a\u0426\u0416\u041a-\u043f\u0440\u043e\u0434\u0443\u0446\u0435\u043d\u0442\u044b (F. prausnitzii, Roseburia) \u2192 \u043f\u0430\u0434\u0430\u0435\u0442 \u0431\u0443\u0442\u0438\u0440\u0430\u0442 \u2192 \u043d\u0435\u0442 HDAC-\u0438\u043d\u0433\u0438\u0431\u0438\u0440\u043e\u0432\u0430\u043d\u0438\u044f \u2192 \u0441\u043d\u0438\u0436\u0430\u0435\u0442\u0441\u044f \u044d\u043a\u0441\u043f\u0440\u0435\u0441\u0441\u0438\u044f TJ-\u0431\u0435\u043b\u043a\u043e\u0432 (ZO-1, \u043e\u043a\u043a\u043b\u044e\u0434\u0438\u043d). \u041e\u0434\u043d\u043e\u0432\u0440\u0435\u043c\u0435\u043d\u043d\u043e \u0440\u0430\u0441\u0442\u0443\u0442 \u0433\u0440\u0430\u043c\u043e\u0442\u0440\u0438\u0446\u0430\u0442\u0435\u043b\u044c\u043d\u044b\u0435 LPS-\u043f\u0440\u043e\u0434\u0443\u0446\u0435\u043d\u0442\u044b \u2192 \u0438\u0437\u0431\u044b\u0442\u043e\u043a \u041b\u041f\u0421 \u2192 TLR4-\u0430\u043a\u0442\u0438\u0432\u0430\u0446\u0438\u044f \u2192 \u043f\u0440\u043e\u0432\u043e\u0441\u043f\u0430\u043b\u0438\u0442\u0435\u043b\u044c\u043d\u044b\u0435 \u0446\u0438\u0442\u043e\u043a\u0438\u043d\u044b \u2192 \u043e\u0442\u043a\u0440\u044b\u0442\u0438\u0435 TJ. \u0414\u0432\u0430 \u043f\u0443\u0442\u0438 \u0441\u0445\u043e\u0434\u044f\u0442\u0441\u044f \u043a \u043e\u0434\u043d\u043e\u043c\u0443 \u0440\u0435\u0437\u0443\u043b\u044c\u0442\u0430\u0442\u0443: leaky gut.\n      <\/div>\n    <\/details>\n    <details style=\"border:1px solid #CBD5E1;border-radius:8px;margin-bottom:8px;overflow:hidden;\">\n      <summary style=\"font-size:15px;font-weight:700;color:#1E293B;padding:14px 18px;cursor:pointer;background:#F8FAFC;list-style:none;display:flex;align-items:center;justify-content:space-between;\">\n        \u041a\u0430\u043a\u043e\u0439 \u0442\u0435\u0441\u0442 \u043c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u043c\u0430 \u043b\u0443\u0447\u0448\u0435 \u0432\u044b\u0431\u0440\u0430\u0442\u044c \u0432 \u0420\u043e\u0441\u0441\u0438\u0438?\n        <span style=\"font-size:20px;color:#1E40AF;font-weight:300;\">+<\/span>\n      <\/summary>\n      <div style=\"padding:14px 18px 16px 18px;background:#FFFFFF;font-size:15px;line-height:1.7;color:#1E293B;\">\n        \u0414\u043b\u044f \u0446\u0435\u043b\u0438 \u00ab\u043e\u0446\u0435\u043d\u0438\u0442\u044c \u0441\u0432\u044f\u0437\u044c \u0441 leaky gut\u00bb: \u043a\u043e\u043c\u043f\u043b\u0435\u043a\u0441\u043d\u044b\u0439 InVivo (\u0437\u043e\u043d\u0443\u043b\u0438\u043d + LBP + \u043c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u043c) \u2014 \u043d\u0430\u0438\u0431\u043e\u043b\u0435\u0435 \u0438\u043d\u0444\u043e\u0440\u043c\u0430\u0442\u0438\u0432\u043d\u044b\u0439. \u0414\u043b\u044f \u0441\u043a\u0440\u0438\u043d\u0438\u043d\u0433\u0430 \u0434\u0438\u0441\u0431\u0438\u043e\u0437\u0430: Atlas Biomed \u2014 \u0445\u043e\u0440\u043e\u0448\u0438\u0439 \u0431\u0430\u043b\u0430\u043d\u0441 \u0446\u0435\u043d\u0430\/\u043a\u0430\u0447\u0435\u0441\u0442\u0432\u043e. \u0414\u043b\u044f \u043c\u0430\u043a\u0441\u0438\u043c\u0430\u043b\u044c\u043d\u043e\u0439 \u0433\u043b\u0443\u0431\u0438\u043d\u044b: Genetico \u0441 WGS. \u0412\u0430\u0436\u043d\u043e: \u043e\u0434\u0438\u043d \u0442\u0435\u0441\u0442 \u2014 \u0441\u043d\u0438\u043c\u043e\u043a. \u041c\u0430\u043a\u0441\u0438\u043c\u0443\u043c \u0438\u043d\u0444\u043e\u0440\u043c\u0430\u0446\u0438\u0438 \u2014 \u0434\u0432\u0430 \u0442\u0435\u0441\u0442\u0430 \u0441 \u0438\u043d\u0442\u0435\u0440\u0432\u0430\u043b\u043e\u043c 12 \u043d\u0435\u0434 (\u0434\u043e\/\u043f\u043e\u0441\u043b\u0435 \u0432\u043c\u0435\u0448\u0430\u0442\u0435\u043b\u044c\u0441\u0442\u0432\u0430).\n      <\/div>\n    <\/details>\n    <details style=\"border:1px solid #CBD5E1;border-radius:8px;margin-bottom:8px;overflow:hidden;\">\n      <summary style=\"font-size:15px;font-weight:700;color:#1E293B;padding:14px 18px;cursor:pointer;background:#F8FAFC;list-style:none;display:flex;align-items:center;justify-content:space-between;\">\n        \u0421\u043a\u043e\u043b\u044c\u043a\u043e \u0432\u0440\u0435\u043c\u0435\u043d\u0438 \u0437\u0430\u043d\u0438\u043c\u0430\u0435\u0442 \u0432\u043e\u0441\u0441\u0442\u0430\u043d\u043e\u0432\u043b\u0435\u043d\u0438\u0435 \u043c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u043c\u0430 \u043f\u0440\u0438 leaky gut?\n        <span style=\"font-size:20px;color:#1E40AF;font-weight:300;\">+<\/span>\n      <\/summary>\n      <div style=\"padding:14px 18px 16px 18px;background:#FFFFFF;font-size:15px;line-height:1.7;color:#1E293B;\">\n        \u041f\u043e \u0434\u0430\u043d\u043d\u044b\u043c RCT: \u0437\u043d\u0430\u0447\u0438\u043c\u044b\u0435 \u0438\u0437\u043c\u0435\u043d\u0435\u043d\u0438\u044f \u0441\u043e\u0441\u0442\u0430\u0432\u0430 \u043c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u0442\u044b \u2014 \u0447\u0435\u0440\u0435\u0437 4\u20138 \u043d\u0435\u0434\u0435\u043b\u044c \u043f\u0440\u0438 \u0440\u0435\u0433\u0443\u043b\u044f\u0440\u043d\u043e\u043c \u043f\u0440\u0438\u0451\u043c\u0435 \u043f\u0440\u043e\u0431\u0438\u043e\u0442\u0438\u043a\u043e\u0432 + \u043f\u0440\u0435\u0431\u0438\u043e\u0442\u0438\u043a\u043e\u0432. \u0424\u0443\u043d\u043a\u0446\u0438\u043e\u043d\u0430\u043b\u044c\u043d\u044b\u0435 \u0438\u0437\u043c\u0435\u043d\u0435\u043d\u0438\u044f (\u2191\u041a\u0426\u0416\u041a, \u2193\u0437\u043e\u043d\u0443\u043b\u0438\u043d) \u2014 8\u201316 \u043d\u0435\u0434\u0435\u043b\u044c. \u0423\u0441\u0442\u043e\u0439\u0447\u0438\u0432\u043e\u0435 \u00ab\u043f\u0435\u0440\u0435\u0441\u0435\u043b\u0435\u043d\u0438\u0435\u00bb \u043d\u043e\u0432\u044b\u0445 \u0448\u0442\u0430\u043c\u043c\u043e\u0432 \u2014 6\u201312 \u043c\u0435\u0441\u044f\u0446\u0435\u0432. \u0411\u0435\u0437 \u0443\u0441\u0442\u0440\u0430\u043d\u0435\u043d\u0438\u044f \u0442\u0440\u0438\u0433\u0433\u0435\u0440\u043e\u0432 (\u0433\u043b\u044e\u0442\u0435\u043d, \u0430\u043b\u043a\u043e\u0433\u043e\u043b\u044c, \u0441\u0442\u0440\u0435\u0441\u0441) \u0432\u043e\u0441\u0441\u0442\u0430\u043d\u043e\u0432\u043b\u0435\u043d\u0438\u0435 \u043d\u0435\u0432\u043e\u0437\u043c\u043e\u0436\u043d\u043e.\n      <\/div>\n    <\/details>\n    <details style=\"border:1px solid #CBD5E1;border-radius:8px;margin-bottom:8px;overflow:hidden;\">\n      <summary style=\"font-size:15px;font-weight:700;color:#1E293B;padding:14px 18px;cursor:pointer;background:#F8FAFC;list-style:none;display:flex;align-items:center;justify-content:space-between;\">\n        \u0421\u0432\u044f\u0437\u0430\u043d \u043b\u0438 \u0434\u044b\u0440\u044f\u0432\u044b\u0439 \u043a\u0438\u0448\u0435\u0447\u043d\u0438\u043a \u0441 \u0434\u0435\u043f\u0440\u0435\u0441\u0441\u0438\u0435\u0439 \u0438 \u0442\u0440\u0435\u0432\u043e\u0436\u043d\u043e\u0441\u0442\u044c\u044e?\n        <span style=\"font-size:20px;color:#1E40AF;font-weight:300;\">+<\/span>\n      <\/summary>\n      <div style=\"padding:14px 18px 16px 18px;background:#FFFFFF;font-size:15px;line-height:1.7;color:#1E293B;\">\n        \u0414\u0430 \u2014 \u0447\u0435\u0440\u0435\u0437 gut-brain axis. \u041b\u041f\u0421 \u0438\u0437 \u0434\u044b\u0440\u044f\u0432\u043e\u0433\u043e \u043a\u0438\u0448\u0435\u0447\u043d\u0438\u043a\u0430 \u2192 \u0430\u043a\u0442\u0438\u0432\u0430\u0446\u0438\u044f \u043c\u0438\u043a\u0440\u043e\u0433\u043b\u0438\u0438 \u2192 \u043d\u0435\u0439\u0440\u043e\u0432\u043e\u0441\u043f\u0430\u043b\u0435\u043d\u0438\u0435 \u2192 \u0441\u043d\u0438\u0436\u0435\u043d\u0438\u0435 BDNF \u0438 \u043d\u0430\u0440\u0443\u0448\u0435\u043d\u0438\u0435 \u0441\u0435\u0440\u043e\u0442\u043e\u043d\u0438\u043d\u043e\u0432\u043e\u0433\u043e \u043c\u0435\u0442\u0430\u0431\u043e\u043b\u0438\u0437\u043c\u0430. \u041c\u0435\u0442\u0430\u0430\u043d\u0430\u043b\u0438\u0437 2021 \u043f\u043e\u043a\u0430\u0437\u0430\u043b: \u0443\u0440\u043e\u0432\u0435\u043d\u044c LBP (\u043c\u0430\u0440\u043a\u0435\u0440 \u044d\u043d\u0434\u043e\u0442\u043e\u043a\u0441\u0435\u043c\u0438\u0438) \u043f\u043e\u0432\u044b\u0448\u0435\u043d \u043f\u0440\u0438 \u0431\u043e\u043b\u044c\u0448\u043e\u043c \u0434\u0435\u043f\u0440\u0435\u0441\u0441\u0438\u0432\u043d\u043e\u043c \u0440\u0430\u0441\u0441\u0442\u0440\u043e\u0439\u0441\u0442\u0432\u0435 (OR 1.8). RCT \u0441 \u043f\u0440\u043e\u0431\u0438\u043e\u0442\u0438\u043a\u0430\u043c\u0438 \u0434\u0435\u043c\u043e\u043d\u0441\u0442\u0440\u0438\u0440\u0443\u044e\u0442 \u0443\u043c\u0435\u0440\u0435\u043d\u043d\u043e\u0435 \u0441\u043d\u0438\u0436\u0435\u043d\u0438\u0435 \u0441\u0438\u043c\u043f\u0442\u043e\u043c\u043e\u0432 \u0442\u0440\u0435\u0432\u043e\u0433\u0438 \u0438 \u0434\u0435\u043f\u0440\u0435\u0441\u0441\u0438\u0438.\n      <\/div>\n    <\/details>\n    <details style=\"border:1px solid #CBD5E1;border-radius:8px;margin-bottom:8px;overflow:hidden;\">\n      <summary style=\"font-size:15px;font-weight:700;color:#1E293B;padding:14px 18px;cursor:pointer;background:#F8FAFC;list-style:none;display:flex;align-items:center;justify-content:space-between;\">\n        \u041c\u043e\u0436\u0435\u0442 \u043b\u0438 \u0434\u0438\u0441\u0431\u0438\u043e\u0437 \u0432\u044b\u0437\u044b\u0432\u0430\u0442\u044c \u0430\u043a\u043d\u0435 \u0438 \u044d\u043a\u0437\u0435\u043c\u0443?\n        <span style=\"font-size:20px;color:#1E40AF;font-weight:300;\">+<\/span>\n      <\/summary>\n      <div style=\"padding:14px 18px 16px 18px;background:#FFFFFF;font-size:15px;line-height:1.7;color:#1E293B;\">\n        \u0414\u0430 \u2014 \u0447\u0435\u0440\u0435\u0437 gut-skin axis. \u0414\u0438\u0441\u0431\u0438\u043e\u0437 \u2192 \u0441\u0438\u0441\u0442\u0435\u043c\u043d\u043e\u0435 \u0432\u043e\u0441\u043f\u0430\u043b\u0435\u043d\u0438\u0435 \u2192 \u0430\u043a\u0442\u0438\u0432\u0430\u0446\u0438\u044f IGF-1 \u0438 mTOR \u0432 \u0441\u0430\u043b\u044c\u043d\u044b\u0445 \u0436\u0435\u043b\u0435\u0437\u0430\u0445 \u2192 \u0433\u0438\u043f\u0435\u0440\u0441\u0435\u0431\u0443\u043c (\u0430\u043a\u043d\u0435). \u041f\u0440\u0438 \u0430\u0442\u043e\u043f\u0438\u0447\u0435\u0441\u043a\u043e\u043c \u0434\u0435\u0440\u043c\u0430\u0442\u0438\u0442\u0435: gut dysbiosis \u043f\u0440\u0435\u0434\u0448\u0435\u0441\u0442\u0432\u0443\u0435\u0442 \u043c\u0430\u043d\u0438\u0444\u0435\u0441\u0442\u0430\u0446\u0438\u0438 \u0443 \u043c\u043b\u0430\u0434\u0435\u043d\u0446\u0435\u0432; \u0441\u043d\u0438\u0436\u0435\u043d\u0438\u0435 Bifidobacterium \u2192 Th2-\u043f\u043e\u043b\u044f\u0440\u0438\u0437\u0430\u0446\u0438\u044f \u2192 \u0430\u0442\u043e\u043f\u0438\u044f. \u041f\u0440\u043e\u0431\u0438\u043e\u0442\u0438\u043a\u0438 (L.rhamnosus GG) \u0434\u043e\u0441\u0442\u043e\u0432\u0435\u0440\u043d\u043e \u0441\u043d\u0438\u0436\u0430\u044e\u0442 SCORAD \u043f\u0440\u0438 \u0410\u0414 \u0432 \u043d\u0435\u0441\u043a\u043e\u043b\u044c\u043a\u0438\u0445 RCT.\n      <\/div>\n    <\/details>\n    <details style=\"border:1px solid #CBD5E1;border-radius:8px;margin-bottom:8px;overflow:hidden;\">\n      <summary style=\"font-size:15px;font-weight:700;color:#1E293B;padding:14px 18px;cursor:pointer;background:#F8FAFC;list-style:none;display:flex;align-items:center;justify-content:space-between;\">\n        \u041f\u043e\u043c\u043e\u0433\u0430\u0435\u0442 \u043b\u0438 FMT (\u0442\u0440\u0430\u043d\u0441\u043f\u043b\u0430\u043d\u0442\u0430\u0446\u0438\u044f \u043a\u0430\u043b\u0430) \u043f\u0440\u0438 leaky gut?\n        <span style=\"font-size:20px;color:#1E40AF;font-weight:300;\">+<\/span>\n      <\/summary>\n      <div style=\"padding:14px 18px 16px 18px;background:#FFFFFF;font-size:15px;line-height:1.7;color:#1E293B;\">\n        FMT \u0434\u043e\u043a\u0430\u0437\u0430\u0442\u0435\u043b\u044c\u043d\u043e \u044d\u0444\u0444\u0435\u043a\u0442\u0438\u0432\u043d\u0430 \u043f\u0440\u0438 C.difficile (\u0440\u0435\u043c\u0438\u0441\u0441\u0438\u044f >90%). \u0414\u043b\u044f leaky gut \/ d\u0438\u0441\u0431\u0438\u043e\u0437\u0430 \u043f\u0440\u0438 leaky gut \u2014 \u0434\u0430\u043d\u043d\u044b\u0435 \u043e\u0433\u0440\u0430\u043d\u0438\u0447\u0435\u043d\u044b (pilot-\u0438\u0441\u0441\u043b\u0435\u0434\u043e\u0432\u0430\u043d\u0438\u044f), \u043d\u043e \u0420\u0424 \u0437\u0430\u043f\u0443\u0441\u043a\u0430\u0435\u0442 \u0441\u0435\u0442\u044c FMT-\u0431\u0430\u043d\u043a\u043e\u0432 \u0432 2025\u20132026 \u0433\u043e\u0434\u0443 \u0441 \u0440\u0430\u0441\u0448\u0438\u0440\u0435\u043d\u0438\u0435\u043c \u043f\u043e\u043a\u0430\u0437\u0430\u043d\u0438\u0439 \u043d\u0430 \u0421\u0420\u041a \u0438 \u0412\u0417\u041a. FMT \u043f\u0440\u0438 leaky gut \u2014 \u043f\u043e\u043a\u0430 \u0432\u043d\u0435 \u0440\u0443\u0442\u0438\u043d\u043d\u043e\u0439 \u043f\u0440\u0430\u043a\u0442\u0438\u043a\u0438, \u043d\u043e \u0430\u043a\u0442\u0438\u0432\u043d\u043e \u0438\u0437\u0443\u0447\u0430\u0435\u0442\u0441\u044f. \u041a\u043e\u043d\u0441\u0443\u043b\u044c\u0442\u0430\u0446\u0438\u044f \u0433\u0430\u0441\u0442\u0440\u043e\u044d\u043d\u0442\u0435\u0440\u043e\u043b\u043e\u0433\u0430 \u043e\u0431\u044f\u0437\u0430\u0442\u0435\u043b\u044c\u043d\u0430.\n      <\/div>\n    <\/details>\n  <\/div>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t\t\t<section class=\"elementor-section elementor-top-section elementor-element elementor-element-129ee19e elementor-section-boxed elementor-section-height-default elementor-section-height-default\" data-id=\"129ee19e\" data-element_type=\"section\" data-e-type=\"section\">\n\t\t\t\t\t\t<div class=\"elementor-container elementor-column-gap-default\">\n\t\t\t\t\t<div class=\"elementor-column elementor-col-100 elementor-top-column elementor-element elementor-element-6af1c9aa\" data-id=\"6af1c9aa\" data-element_type=\"column\" data-e-type=\"column\">\n\t\t\t<div class=\"elementor-widget-wrap elementor-element-populated\">\n\t\t\t\t\t\t<div class=\"elementor-element elementor-element-1b257222 elementor-widget-divider--view-line elementor-widget elementor-widget-divider\" data-id=\"1b257222\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"divider.default\">\n\t\t\t\t\t\t\t<div class=\"elementor-divider\">\n\t\t\t<span class=\"elementor-divider-separator\">\n\t\t\t\t\t\t<\/span>\n\t\t<\/div>\n\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t<\/section>\n\t\t<div class=\"elementor-element elementor-element-c3cef2c e-flex e-con-boxed e-con e-parent\" data-id=\"c3cef2c\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-2db4e33 elementor-widget elementor-widget-text-editor\" data-id=\"2db4e33\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"text-editor.default\">\n\t\t\t\t\t\t\t\t\t<p style=\"text-align: center; color: #718096; font-size: 14px;\"><img decoding=\"async\" class=\"emoji\" role=\"img\" draggable=\"false\" src=\"https:\/\/s.w.org\/images\/core\/emoji\/17.0.2\/svg\/1f468-200d-2695-fe0f.svg\" alt=\"\ud83d\udc68\u200d\u2695\ufe0f\" \/> <a href=\"https:\/\/novolakrb1.ru\/o-bolnitse\/meditsinskii-personal\">\u0414\u043e\u043a\u0442\u043e\u0440 \u0421\u0443\u043b\u0435\u0439\u043c\u0430\u043d\u043e\u0432\u0430 \u0411.\u041d.<\/a> | <img decoding=\"async\" class=\"emoji\" role=\"img\" draggable=\"false\" src=\"https:\/\/s.w.org\/images\/core\/emoji\/17.0.2\/svg\/1f4c5.svg\" alt=\"\ud83d\udcc5\" \/> 01.05.2026 | <img decoding=\"async\" class=\"emoji\" role=\"img\" draggable=\"false\" src=\"https:\/\/s.w.org\/images\/core\/emoji\/17.0.2\/svg\/23f1.svg\" alt=\"\u23f1\" \/> 15 \u043c\u0438\u043d \u0447\u0442\u0435\u043d\u0438\u044f<\/p>\t\t\t\t\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-2598826 e-flex e-con-boxed e-con e-parent\" data-id=\"2598826\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-e88a757 elementor-widget elementor-widget-html\" data-id=\"e88a757\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<!-- \u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\r\n     \u0411\u041b\u041e\u041a 1 \u00b7 \u041c\u0415\u0414\u0418\u0426\u0418\u041d\u0421\u041a\u0418\u0419 \u0414\u0418\u0421\u041a\u041b\u0415\u0419\u041c\u0415\u0420\r\n     \u0420\u0430\u0437\u043c\u0435\u0449\u0430\u0439\u0442\u0435 \u0432 \u043d\u0430\u0447\u0430\u043b\u0435 \u0438\u043b\u0438 \u043a\u043e\u043d\u0446\u0435 \u043a\u0430\u0436\u0434\u043e\u0439 \u0441\u0442\u0430\u0442\u044c\u0438\r\n     \u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550 -->\r\n\r\n<style>\r\n.mdblog-disclaimer {\r\n  border-left: 4px solid #2a9d8f;\r\n  background: #f0faf9;\r\n  border-radius: 0 8px 8px 0;\r\n  padding: 20px 24px;\r\n  margin: 28px 0;\r\n  font-family: inherit;\r\n  box-sizing: border-box;\r\n}\r\n.mdblog-disclaimer__head {\r\n  display: flex;\r\n  align-items: center;\r\n  gap: 10px;\r\n  margin-bottom: 10px;\r\n}\r\n.mdblog-disclaimer__title {\r\n  font-size: 15px;\r\n  font-weight: 600;\r\n  color: #0f6e56;\r\n  margin: 0;\r\n  line-height: 1.3;\r\n}\r\n.mdblog-disclaimer__text {\r\n  font-size: 14px;\r\n  line-height: 1.7;\r\n  color: #374151;\r\n  margin: 0;\r\n}\r\n.mdblog-disclaimer__text strong {\r\n  font-weight: 600;\r\n  color: #1a5c6b;\r\n}\r\n<\/style>\r\n\r\n<div class=\"mdblog-disclaimer\" role=\"note\" aria-label=\"\u041c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u0438\u0439 \u0434\u0438\u0441\u043a\u043b\u0435\u0439\u043c\u0435\u0440\">\r\n  <div class=\"mdblog-disclaimer__head\">\r\n    <svg width=\"20\" height=\"20\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"#2a9d8f\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\" aria-hidden=\"true\">\r\n      <circle cx=\"12\" cy=\"12\" r=\"10\"\/>\r\n      <line x1=\"12\" y1=\"8\" x2=\"12\" y2=\"12\"\/>\r\n      <circle cx=\"12\" cy=\"16\" r=\"0.5\" fill=\"#2a9d8f\"\/>\r\n    <\/svg>\r\n    <p class=\"mdblog-disclaimer__title\">\u0412\u0430\u0436\u043d\u0430\u044f \u0438\u043d\u0444\u043e\u0440\u043c\u0430\u0446\u0438\u044f<\/p>\r\n  <\/div>\r\n  <p class=\"mdblog-disclaimer__text\">\r\n    \u041c\u0430\u0442\u0435\u0440\u0438\u0430\u043b\u044b \u044d\u0442\u043e\u0433\u043e \u0431\u043b\u043e\u0433\u0430 \u043d\u043e\u0441\u044f\u0442 <strong>\u0438\u0441\u043a\u043b\u044e\u0447\u0438\u0442\u0435\u043b\u044c\u043d\u043e \u0438\u043d\u0444\u043e\u0440\u043c\u0430\u0446\u0438\u043e\u043d\u043d\u044b\u0439 \u0438 \u043e\u0431\u0440\u0430\u0437\u043e\u0432\u0430\u0442\u0435\u043b\u044c\u043d\u044b\u0439 \u0445\u0430\u0440\u0430\u043a\u0442\u0435\u0440<\/strong> \u0438 \u043d\u0435 \u044f\u0432\u043b\u044f\u044e\u0442\u0441\u044f \u043c\u0435\u0434\u0438\u0446\u0438\u043d\u0441\u043a\u043e\u0439 \u043a\u043e\u043d\u0441\u0443\u043b\u044c\u0442\u0430\u0446\u0438\u0435\u0439, \u043f\u043e\u0441\u0442\u0430\u043d\u043e\u0432\u043a\u043e\u0439 \u0434\u0438\u0430\u0433\u043d\u043e\u0437\u0430 \u0438\u043b\u0438 \u043d\u0430\u0437\u043d\u0430\u0447\u0435\u043d\u0438\u0435\u043c \u043b\u0435\u0447\u0435\u043d\u0438\u044f. \u0410\u0432\u0442\u043e\u0440 \u2014 \u043f\u0440\u0430\u043a\u0442\u0438\u043a\u0443\u044e\u0449\u0438\u0439 \u0432\u0440\u0430\u0447, \u043e\u0434\u043d\u0430\u043a\u043e \u043f\u0443\u0431\u043b\u0438\u043a\u0443\u0435\u043c\u044b\u0435 \u0441\u0442\u0430\u0442\u044c\u0438 \u043d\u0435 \u0437\u0430\u043c\u0435\u043d\u044f\u044e\u0442 \u0438\u043d\u0434\u0438\u0432\u0438\u0434\u0443\u0430\u043b\u044c\u043d\u043e\u0433\u043e \u043f\u0440\u0438\u0451\u043c\u0430 \u0441\u043f\u0435\u0446\u0438\u0430\u043b\u0438\u0441\u0442\u0430. \u0418\u043d\u0442\u0435\u0440\u043f\u0440\u0435\u0442\u0430\u0446\u0438\u044f \u043b\u0430\u0431\u043e\u0440\u0430\u0442\u043e\u0440\u043d\u044b\u0445 \u043f\u043e\u043a\u0430\u0437\u0430\u0442\u0435\u043b\u0435\u0439, \u0440\u0435\u0444\u0435\u0440\u0435\u043d\u0441\u043d\u044b\u0445 \u0437\u043d\u0430\u0447\u0435\u043d\u0438\u0439 \u0438 \u0431\u0438\u043e\u043c\u0430\u0440\u043a\u0435\u0440\u043e\u0432 \u0432\u0441\u0435\u0433\u0434\u0430 \u0434\u043e\u043b\u0436\u043d\u0430 \u043f\u0440\u043e\u0432\u043e\u0434\u0438\u0442\u044c\u0441\u044f \u0432\u0430\u0448\u0438\u043c \u043b\u0435\u0447\u0430\u0449\u0438\u043c \u0432\u0440\u0430\u0447\u043e\u043c \u0441 \u0443\u0447\u0451\u0442\u043e\u043c \u043f\u043e\u043b\u043d\u043e\u0439 \u043a\u043b\u0438\u043d\u0438\u0447\u0435\u0441\u043a\u043e\u0439 \u043a\u0430\u0440\u0442\u0438\u043d\u044b. <strong>\u041d\u0435 \u0437\u0430\u043d\u0438\u043c\u0430\u0439\u0442\u0435\u0441\u044c \u0441\u0430\u043c\u043e\u0434\u0438\u0430\u0433\u043d\u043e\u0441\u0442\u0438\u043a\u043e\u0439 \u0438 \u0441\u0430\u043c\u043e\u043b\u0435\u0447\u0435\u043d\u0438\u0435\u043c.<\/strong>\r\n  <\/p>\r\n<\/div>\r\n\r\n<!-- \u041a\u043e\u043d\u0435\u0446 \u0431\u043b\u043e\u043a\u0430 1 -->\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t<div class=\"elementor-element elementor-element-ccafcb1 e-flex e-con-boxed e-con e-parent\" data-id=\"ccafcb1\" data-element_type=\"container\" data-e-type=\"container\">\n\t\t\t\t\t<div class=\"e-con-inner\">\n\t\t\t\t<div class=\"elementor-element elementor-element-dbe7ecb elementor-widget elementor-widget-html\" data-id=\"dbe7ecb\" data-element_type=\"widget\" data-e-type=\"widget\" data-widget_type=\"html.default\">\n\t\t\t\t\t<!-- \u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\r\n     \u0411\u041b\u041e\u041a 2 \u00b7 \u041e\u0422\u0421\u0423\u0422\u0421\u0422\u0412\u0418\u0415 \u041a\u041e\u041d\u0424\u041b\u0418\u041a\u0422\u0410 \u0418\u041d\u0422\u0415\u0420\u0415\u0421\u041e\u0412\r\n     \u0420\u0430\u0437\u043c\u0435\u0449\u0430\u0439\u0442\u0435 \u0432 \u043a\u043e\u043d\u0446\u0435 \u0441\u0442\u0430\u0442\u044c\u0438 \u0438\u043b\u0438 \u043d\u0430 \u0441\u0442\u0440\u0430\u043d\u0438\u0446\u0435 \u00ab\u041e\u0431 \u0430\u0432\u0442\u043e\u0440\u0435\u00bb\r\n     \u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550\u2550 -->\r\n\r\n<style>\r\n.mdblog-coi {\r\n  border: 1px solid #d1fae5;\r\n  background: #f0fdf4;\r\n  border-radius: 8px;\r\n  padding: 18px 22px;\r\n  margin: 24px 0;\r\n  font-family: inherit;\r\n  box-sizing: border-box;\r\n}\r\n.mdblog-coi__head {\r\n  display: flex;\r\n  align-items: center;\r\n  gap: 10px;\r\n  margin-bottom: 8px;\r\n}\r\n.mdblog-coi__title {\r\n  font-size: 14px;\r\n  font-weight: 600;\r\n  color: #065f46;\r\n  margin: 0;\r\n  text-transform: uppercase;\r\n  letter-spacing: 0.06em;\r\n}\r\n.mdblog-coi__text {\r\n  font-size: 13.5px;\r\n  line-height: 1.65;\r\n  color: #374151;\r\n  margin: 0;\r\n}\r\n.mdblog-coi__text a {\r\n  color: #0f6e56;\r\n  text-decoration: underline;\r\n  text-underline-offset: 3px;\r\n}\r\n<\/style>\r\n\r\n<div class=\"mdblog-coi\" role=\"note\" aria-label=\"\u041a\u043e\u043d\u0444\u043b\u0438\u043a\u0442 \u0438\u043d\u0442\u0435\u0440\u0435\u0441\u043e\u0432\">\r\n  <div class=\"mdblog-coi__head\">\r\n    <svg width=\"18\" height=\"18\" viewBox=\"0 0 24 24\" fill=\"none\" stroke=\"#059669\" stroke-width=\"2\" stroke-linecap=\"round\" stroke-linejoin=\"round\" aria-hidden=\"true\">\r\n      <path d=\"M22 11.08V12a10 10 0 1 1-5.93-9.14\"\/>\r\n      <polyline points=\"22 4 12 14.01 9 11.01\"\/>\r\n    <\/svg>\r\n    <p class=\"mdblog-coi__title\">\u041a\u043e\u043d\u0444\u043b\u0438\u043a\u0442 \u0438\u043d\u0442\u0435\u0440\u0435\u0441\u043e\u0432<\/p>\r\n  <\/div>\r\n  <p class=\"mdblog-coi__text\">\r\n    \u0410\u0432\u0442\u043e\u0440 \u0437\u0430\u044f\u0432\u043b\u044f\u0435\u0442 \u043e\u0431 \u043e\u0442\u0441\u0443\u0442\u0441\u0442\u0432\u0438\u0438 \u043a\u043e\u043d\u0444\u043b\u0438\u043a\u0442\u0430 \u0438\u043d\u0442\u0435\u0440\u0435\u0441\u043e\u0432. \u0411\u043b\u043e\u0433 \u043d\u0435 \u0444\u0438\u043d\u0430\u043d\u0441\u0438\u0440\u0443\u0435\u0442\u0441\u044f \u0444\u0430\u0440\u043c\u0430\u0446\u0435\u0432\u0442\u0438\u0447\u0435\u0441\u043a\u0438\u043c\u0438 \u043a\u043e\u043c\u043f\u0430\u043d\u0438\u044f\u043c\u0438, \u043f\u0440\u043e\u0438\u0437\u0432\u043e\u0434\u0438\u0442\u0435\u043b\u044f\u043c\u0438 \u043b\u0430\u0431\u043e\u0440\u0430\u0442\u043e\u0440\u043d\u043e\u0433\u043e \u043e\u0431\u043e\u0440\u0443\u0434\u043e\u0432\u0430\u043d\u0438\u044f, \u0411\u0410\u0414-\u0431\u0440\u0435\u043d\u0434\u0430\u043c\u0438 \u0438\u043b\u0438 \u0438\u043d\u044b\u043c\u0438 \u043a\u043e\u043c\u043c\u0435\u0440\u0447\u0435\u0441\u043a\u0438\u043c\u0438 \u0441\u0442\u0440\u0443\u043a\u0442\u0443\u0440\u0430\u043c\u0438, \u0437\u0430\u0438\u043d\u0442\u0435\u0440\u0435\u0441\u043e\u0432\u0430\u043d\u043d\u044b\u043c\u0438 \u0432 \u0441\u043e\u0434\u0435\u0440\u0436\u0430\u043d\u0438\u0438 \u043f\u0443\u0431\u043b\u0438\u043a\u0430\u0446\u0438\u0439. \u0420\u0435\u043a\u043b\u0430\u043c\u043d\u044b\u0435 \u0438\u043b\u0438 \u0441\u043f\u043e\u043d\u0441\u043e\u0440\u0441\u043a\u0438\u0435 \u043c\u0430\u0442\u0435\u0440\u0438\u0430\u043b\u044b, \u0435\u0441\u043b\u0438 \u0442\u0430\u043a\u043e\u0432\u044b\u0435 \u043f\u043e\u044f\u0432\u044f\u0442\u0441\u044f, \u0431\u0443\u0434\u0443\u0442 \u044f\u0432\u043d\u043e \u043e\u0431\u043e\u0437\u043d\u0430\u0447\u0435\u043d\u044b \u043a\u0430\u043a \u0442\u0430\u043a\u043e\u0432\u044b\u0435. \u0421\u0441\u044b\u043b\u043a\u0438 \u043d\u0430 \u043b\u0430\u0431\u043e\u0440\u0430\u0442\u043e\u0440\u0438\u0438, \u0430\u043d\u0430\u043b\u0438\u0437\u0430\u0442\u043e\u0440\u044b \u0438 \u043f\u0440\u0435\u043f\u0430\u0440\u0430\u0442\u044b \u043f\u0440\u0438\u0432\u043e\u0434\u044f\u0442\u0441\u044f \u0438\u0441\u043a\u043b\u044e\u0447\u0438\u0442\u0435\u043b\u044c\u043d\u043e \u0432 \u043e\u0431\u0440\u0430\u0437\u043e\u0432\u0430\u0442\u0435\u043b\u044c\u043d\u044b\u0445 \u0446\u0435\u043b\u044f\u0445 \u0431\u0435\u0437 \u043a\u043e\u043c\u043c\u0435\u0440\u0447\u0435\u0441\u043a\u043e\u0439 \u0430\u0444\u0444\u0438\u043b\u0438\u0440\u043e\u0432\u0430\u043d\u043d\u043e\u0441\u0442\u0438.\r\n  <\/p>\r\n<\/div>\r\n\r\n<!-- \u041a\u043e\u043d\u0435\u0446 \u0431\u043b\u043e\u043a\u0430 2 -->\r\n\t\t\t\t<\/div>\n\t\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t\t\t<\/div>\n\t\t","protected":false},"excerpt":{"rendered":"<p>\u041c\u0438\u043a\u0440\u043e\u0431\u0438\u043e\u043c \u043a\u0438\u0448\u0435\u0447\u043d\u0438\u043a\u0430 \u0438 \u0434\u044b\u0440\u044f\u0432\u044b\u0439 \u043a\u0438\u0448\u0435\u0447\u043d\u0438\u043a: \u0434\u0438\u0441\u0431\u0438\u043e\u0437, \u0442\u0435\u0441\u0442\u044b \u0438 \u043f\u0440\u043e\u0442\u043e\u043a\u043e\u043b \u0432\u043e\u0441\u0441\u0442\u0430\u043d\u043e\u0432\u043b\u0435\u043d\u0438\u044f \u0413\u043b\u0430\u0432\u043d\u0430\u044f \u203a \u0421\u0442\u0430\u0442\u044c\u0438 \u203a \u00a0\u0417\u0434\u043e\u0440\u043e\u0432\u044c\u0435 \u043a\u0438\u0448\u0435\u0447\u043d\u0438\u043a\u0430 \u203a \u0414\u044b\u0440\u044f\u0432\u044b\u0439 \u043a\u0438\u0448\u0435\u0447\u043d\u0438\u043a \u203a 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